The ability of some microbes, such as Trypanosoma or Giardia to alter their surface molecules
and evade destruction by the host's antibodies is called
A) antigenic variation.
B) lysogenic conversion.
C) virulence.
D) cytopathic effect.
E) cytocidal effect - ANSantigenic variation
Most pathogens that gain access through the skin
A) can penetrate intact skin.
B) just infect the skin itself.
C) enter through hair follicles and sweat ducts.
D) must adhere first while their invasive factors allow them to penetrate.
E) must be injected - ANSenter through hair follicles and sweat ducts
The ID50 is
A) a measure of pathogenicity.
B) the dose that will cause an infection in 50 percent of the test population.
C) the dose that will kill some of the test population.
D) the dose that will cause an infection in some of the test population.
E) the dose that will kill 50 percent of the test population - ANSthe dose that will cause an
infection in 50 percent of the test population
All of the following contribute to a pathogen's invasiveness EXCEPT
A) toxins.
B) capsules.
C) cell wall components.
D) hyaluronidase.
E) coagulases - ANStoxins
Which of the following statements is FALSE?
A) Leukocidins destroy neutrophils.
B) Hemolysins lyse red blood cells.
C) Hyaluronidase breaks down substances between cells.
D) Kinase destroys fibrin clots.
E) Coagulase destroys blood clots - ANSCoagulase destroys blood clots
- ANSthey are resistant to heat
, Endotoxins are
A) associated with gram-positive bacteria.
B) molecules that bind nerve cells.
C) part of the gram-negative cell wall.
D) excreted from the cell.
E) A-B toxins - ANSpart of the gram-negative cell wall
Which of the following is NOT a membrane-disrupting toxin?
A) A-B toxin
B) hemolysin
C) leukocidin
D) streptolysin O
E) streptolysin S - ANSA-B toxin
Cytopathic effects are changes in host cells due to
A) viral infections.
B) protozoan infections.
C) fungal infections.
D) bacterial infections.
E) helminthic infections - ANSviral infections
Which of the following does NOT contribute to the symptoms of a fungal disease?
A) capsules
B) toxins
C) allergic response of the host
D) cell walls
E) metabolic products - ANScell walls
All of the following are methods of avoiding host antibodies EXCEPT
A) antigenic changes.
B) IgA proteases.
C) invasins.
D) membrane-disrupting toxins.
E) inducing endocytosis - ANSmembrane-disrupting toxins
Siderophores are bacterial proteins that compete with the host's
A) antibodies.
B) red blood cells.
C) iron-transport proteins.
D) white blood cells.
E) receptors - ANSiron-transport proteins
The fimbriae of Neisseria gonorrhea and enteropathogenic E. coli are examples of
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