• transport cellulaire PLAQUE
DESMOSOMALE
• perméable a l'eau + sub dissoutes
• necessite une ZA pour se mettre en place
• cadhérine homophile
• aspect pentalamellaire MET
• pls / cellule
• transport paracellulaire par relachement des claudines
•
• présent dans crtn type de cellules (epithelliale,
• marquée par une crete jonctionelle
nb: desmogléine / desmocioline = Cadhérine
mémo : Claudine adore aller au zoo voir les singe et les otaries
claudine actine ZO cinguline Occludine
• hyper phosphorylation caténine β : dessablemblage de jonction :
passage select de metabolites
Zonula adhérence (ZA) : 15-20 nm • lié au terminal web lui meme lié au cmplx actine / myosine
• intervention dans la contraction muscu
•
actine prot de liaison Caténine β Caténine P120
Cadhérine E (CAM )--------
Ca2+
MEC
a
• calcium dep
• cadhérine
• caténine P120: Fixation Cadh E = Stabilisation
• caténine β :ancrage?
le
Mg2+
Col 4
• calcium / magnésium dependant
col 7 col7 col7 • !! porteines apparentées à desmoplakine et plakoglobine
col 1
MEC
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