WGU 785 Final Exam/125 Questions And answers/100%
Correct
Hemophilia Pedigree - Father has hemophilia, mother does not. What is the outcome
for their kids? - Correct answer -His daughters would be carriers. This is x-link
recessive.
Autosomal:
Dominant: - Correct answer -Autosomal: males a...
WGU 785 Final Exam/125 Questions And answers/100%
Correct
Hemophilia Pedigree - Father has hemophilia, mother does not. What is the outcome
for their kids? - Correct answer -His daughters would be carriers. This is x-link
recessive.
polymerase chain reaction (PCR) - Correct answer -The process of copying DNA in the
lab. Uses Template DNA, Nucleotides (dNTPS), DNA Polymerase, and DNA primers.
3 Steps of PCR - Correct answer -1. Denaturation: DNA is heated to 95C to separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to copy and
add DNA polymerase.
3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides building
a new DNA strand.
Base Excision Repair (BER) - Correct answer -How you repair a mutation. BER is used to
repair damage to a base caused by harmful molecules. You remove the base that is
damaged and replace it. *BER removes a single nucleotide*
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: - Correct answer -replication. DNA polymerase
proofreads but sometimes a mismatch pair gets through. MMR removes a large section
of the nucleotides from the new DNA and DNA polymerase tries again. (Ex: C-T instead
of C-A)
, Mismatch Repair corrects what kind of DNA damage? - Correct answer -When a base is
mismatched due to errors in replication. Such as G-T instead of G-C. DNA polymerase
comes by and fixes it.
What happens when DNA polymerase binds to DNA to make RNA? - Correct answer -
TRANSCRIPTION! DNA polymerase takes the individual nucleotides and matches them
to the parental sequences to ensure a correct pair. It must bind with RNA primer to
work.
What is needed for DNA replication? - Correct answer -DNA polymerase
Nonsense Mutation - Correct answer -Change in 1 nucleotide produces a STOP codon
Stop= nonsense because it is no more.
Silent Mutation - Correct answer -Change in 1 nucleotide but codes for the same amino
acid. Silent= the change doesn't change the name of the protein
Missense Mutation - Correct answer -Change in 1 nucleotide leads to a code for a
different amino acid. Missense = mistake was made.
What happends during RNA splicing? - Correct answer -During RNA splicing introns are
cut out, the remaining exons are joined together.
5'ATG AGT CTC TCT 3'
Find the DNA template strand. - Correct answer -3'TAC TCA GAG AGA 5'
The DNA template strand is complimentary. So start with the opposite number, then go
L-R with the complimentary letter.
5'ATG AGT CTC TCT 3'
What is the corresonding mRNA sequence? - Correct answer -5'AUG AGU CUC UCU 3'
This sequence is the same as the coding strand except T changes to U because it is
RNA. RNA doesn't have T.
How would a mutation from CTC to ATC affect the protein sequence? (CTC/ATC -
coding strand, AUC - mRNA strand) - Correct answer -This will make a missense
mutation because it changes the name of the protein. (look at the chart provided.)
missense = mistake
DNA replication process - Correct answer -DNA ->Transcription -> RNA -> Translation -
> Polypeptide
Describe how you would find what ionized Alanine looks like. - Correct answer -This is
an amino acid. Look for the "R" group. Alanine is a hydrophobic amino acid that has
CH3. It is a weak interaction. An ionized acid will have a + or - charge.
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