LS 2 PG DIP UCL pharmacy diploma (LIVER TEST ONLY) PHAY0042
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Course
ULC ECONS
Institution
AQA
In the liver what is the role of the gall bladder ?
your gall bladder where bile is produced and transported via the bile duct releasing the bile into the
duodenum
Answer = Bile production
What is the definition of cholestasis
Cholestasis = The reduced bile secretion or flow due to problem wit...
LS 2 PG DIP UCL pharmacy diploma
(LIVER TEST ONLY) PHAY0042
In the liver what is the role of the gall bladder ?
your gall bladder where bile is produced and transported via the bile duct releasing the bile into the
duodenum
Answer = Bile production
What is the definition of cholestasis
Cholestasis = The reduced bile secretion or flow due to problem with hepatocytes production of bile
acid
or
a blockage of the gall bladder or associated ducts that help transport bile.
The liver has metabolic, synthetic and excretory functions, what are the metabolic functions of the liver
?
Metabolic functions of the liver are :-
a) Converts glucose into glycogen for storage
b) The liver is also involved in the metabolism and excretion of drugs and toxins
c) The liver also causes hormone inactivation
The liver has metabolic, synthetic and excretory functions, what are the synthetic functions of the liver
?
, 1.) production of bile – bile helps to carry away waste and break down fats in the small intestine during
disgestion
bile helps the absorption of fat and fat soluble vitamins particularly ADEK – you need bile to be able to
absorb those fat soluble vitamins
2.) the liver is also involved in the synthesis and metabolism of cholesterol, phospholioids,
triglycerides, lipoproteins
3.) the liver also produces plasma proteins
4.) the liver is involved in the synthesis of clotting factors
5.) the liver is also involved in the regulation of blood levels of amino acids
The liver has metabolic, synthetic and excretory functions, what are the excretory functions of the liver
?
Excretory functions
1.) the liver converts posinous ammonia to urea which can then be excreted out as urine
2.) the liver is also involved in the conjugation and excretion of bilirubin
What is bilirubin ?
bilirubin is the breakdown product of red blood cells from haem - in haemoglobin
Haem needs to be made more soluble - so it needs to undergo conjugation in the liver to make it more
soluble so it can be mixed with bile via the bile duct into the duodenum and excreted out.
If we have raised bilirubin in a patient it may be due to pre hepatic issues - intra hepatic issues or post
hepatic issues
what is meant by pre hepatic issues ?
Over production of bilirubin or impaired uptake of the bilirubin by the liver to be conjugated
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