Samenvatting hart en vaten 1-prof. Heidbuchel-2e Bach
36 views 0 purchase
Course
Hart en vaten 1 (1026GENGE2)
Institution
Universiteit Antwerpen (UA)
Een samenvatting van Hart en Vaten 1, gegeven in het eerste semester van Ba2 gegeven door H. Heidbuchel en enkele gastprofessoren.
Behaald resultaat 17/20
........................................................................................................................................................................... 34
Interac?e vasculaire en cardiale func?e curve: ....................................................................................................... 35
Inspanning: interac?es curves ................................................................................................................................. 35
Chronisch harWalen: interac?es curves.................................................................................................................... 35
Me?ng van de CVD: ................................................................................................................................................. 36
Neurohumorale controle hart en circula<e: ........................................................................................................ 36
Controle via autonoom zenuwstelsel.................................................................................................................. 36
Autonoom zenuwstelsel: .......................................................................................................................................... 36
Adrenerge en muscarine receptoren in het hart en bloedvaten: ............................................................................. 37
Ligging van de arteriële baroreceptoren: ................................................................................................................ 38
Belangrijkste reflexen: ........................................................................................................................................ 38
Brainbridge reflex: ................................................................................................................................................... 38
Chemoreceptoren: ................................................................................................................................................... 38
CNS: ischemic respons ............................................................................................................................................. 38
Cushing reflex: ......................................................................................................................................................... 39
Pijnreflexen: ............................................................................................................................................................. 39
Bezold-jarisch reflex: ................................................................................................................................................ 39
Stretch receptoren: .................................................................................................................................................. 39
Duik reflex: ............................................................................................................................................................... 39
Humorale controle: ............................................................................................................................................. 40
Effect catecholamines: ............................................................................................................................................. 40
Syncope: ............................................................................................................................................................. 42
Vasovagale syncope:................................................................................................................................................ 42
Head up ?l?ng test: ................................................................................................................................................. 43
Vasovagale syncope:................................................................................................................................................ 44
Syncope tgv orthosta?sche hypotensie: .................................................................................................................. 44
Cardiovasculaire aanpassingen bij inspanning: .................................................................................................... 44
Aanpassingen: ......................................................................................................................................................... 44
Orgaandoorbloeding bij inspanning: ....................................................................................................................... 45
Mechanismen bij inspanning: .................................................................................................................................. 45
Veranderingen hemodynamica: .............................................................................................................................. 45
Factoren met invloeden op de CV aanpassingen: .................................................................................................... 45
Orgaanperfusie: .................................................................................................................................................. 46
DistribuGe van het hartdebiet per orgaan: ......................................................................................................... 46
Pathologie van de lymfecircula<e:....................................................................................................................... 73
Anatomie: ................................................................................................................................................................ 73
Func?es van het lymfa?sch systeem: ...................................................................................................................... 73
Pathologie lymfoedeem: .......................................................................................................................................... 74
,Inleiding cardiovasculair systeem
Schikking organen en vaatbedden:
• Pulmonale en systeem-circula1e in serie
(Maw pompen eenzelfde debiet, wat binnenkomt wordt terug uitgepompt)
• Circula1e orgaansystemen gebeurt in parallel
- Lever staat in serie met gastro-intes1nale tractus
- Auto-regula1e
• Verband druk, debiet, vaatweerstand: F=P/R
- Weerstanden in parallel: 1/R1+2/R2+…
- Weerstanden in serie: R1+R2+…
• Bestaat uit endotheel omgeven door basaalmembraan
1. Con1nu capillair:
- Con1nu basaal membraan
- Pericyten (gladde spiercel)
- Verbinding door 1ght junc1ons en transport door transcytose (caveolae)
§ Voorbeeld: alveolaire wanden
2. Gefenestreerd capillair:
- Fenestrae met of zonder diafragma
§ Voorbeeld mét: darmwand
§ Voorbeeld zonder: nier glomeruli
3. Discon1nu capillair (=sinusoïden):
- Onderbrekingen in het capillair groot
- Discon1nu basaal membraan
Venen:
• Wandlagen:
- Géén m. elas1ca interna
- Tunica media: meer collagene vezels
- Tunica muscularis dunner
- Kleppen
, 1. Post-capillaire venulen:
- Diapedese (d.m.v. selec1nes en integrines)
- Hoog-endotheliale venulen in lymfoide organen
2. Musculaire venulen
Lymfevaten:
1. Lymfa1sche capillairen:
- Endotheel
- Geen volledig basaal membraan
- Aanwezig in alle weefsels, behalve: kraakbeen, bot, epitheel, CZS, beenmerg
2. Grotere lymfevaten: (cfr venen)
- Tunica in1ma
- Tunica media
- Tunica adven11a
- Met kleppen en lymfeklieren
Overzicht Hart:
Wandlagen:
• Hartskelet:
- Dicht collageen bindweefsel
- Scheiding atria/ventrikels
- Aanhech1ng kleppen
- Annuli fibrosi, trigona fibrosa, septum membranaceum
• Endocard:
- Rond de atria, ventrikels en kleppen
- Binnenste laag: endotheel en subendotheliaal bindweefsel
- Middelste laag: gladde spiervezels en elas1sche
- Buitenste laag: bindweefsel, bloedvaten en adipocyten
• Myocard:
- Rond het hartspierweefsel
- Ertussen het endomysium: bindweefsel met capillairen
- Niet gefuseerde cellen en veel mitochondria
- Intercalaire schijven (gap junc1ons, 1ght junc1ons en desmosomen)
- Gespecialiseerde cardiocyten
§ Myo-endocriene cardiocyten (produc1e ANF)
§ Nodale cardiocyten
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller vM1vH. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.65. You're not tied to anything after your purchase.