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Evolutionary relationships and natural selection mechanism

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Natural selection, mutation, genetic drift, and gene flow drive the process of evolution. Evolution is the process by which populations change over time. When we talk about how populations change in an evolutionary sense, we're generally talking about the frequency of different alleles within that ...

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  • February 18, 2024
  • 19
  • 2023/2024
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  • Nyongesa
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LECTURE 6: Molecular Evolution



DR. BENSON O. NYONGESA




02/18/2024

, Molecular Evolution
Definition:
• Evolutionary change at the level of the DNA sequence.

 Deals with the rates of sequence change, relative importanc
adaptive and neutral changes, and changes in genome struct




02/18/2024

, Terms in molecular Evolution
• Speciation: Evolution of a new gene/protein that is genetica
independent of the ancestral gene from which it arose.
• Homolog: A gene/protein related to a second gene/protein by
descent from a common ancestral gene by speciation.

• Ortholog: Genes in different species that have evolved throu
speciation events only and retain same function.
• How do you determine if a gene is ortholog?
 By collecting all the genes in the two species and comparing
all to one another.
 If genes from the 2 species identify each other as their partne
then they are considered orthologs.
02/18/2024

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