Fisiopatologia del dengue (actualizacion )- Angente etiologico, fisiopatologia, clinica, diagnostico y tratamiento, clase de pacientes.
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Course
2301
Institution
Universidad Nacional Experimental Romulo Gallegos
En vista de los pocos resultados relevante referente al tema, he decidido subir este resumen resultado de mi lectura basada en diferentes literaturas.
-- Dengue:
- Etiologia.
- Fisiopatologia (patogenia y patologia).
- Clinica.
- Clase de pacientes.
- Diagnostico.
- Tratamiento.
Aedes albopicatus DENV - 3
Virus del dengue: DEN o DENV DENV - 4
RNA monocatenario Dura semanas a pocos meses
Genero flavivirus, familia flaviviridae Inmunidad homologa permanent
Aumento dependiente de anticuerpos (ADE):
Diurnos Replicación en intestino
medio y glándulas salivales
Anticuerpos PROBABILIDAD DE No viven en la selva
Es sano
FENGUE GRAVE
Efectividad
Infectividad
Se infecta al picar los humanos
De un nuevo serotipo
, Partícula madura: Esférica -SEROTIPOS:
Nucleocápside icosaédrica
DENV - 1
Proteína C M. viral DENV - 2
DENV - 3
Cápside
DENV - 4
- Familia flaviviridae ARN vírico
- Géneros:
Genoma de ARN monocatenar
de polaridad positiva
Pestivirus
Virus de la hepatitis B
Flavivirus
Proteína E:
- Virus de la f. amarilla
Envoltura que deriva d
- Virus de la encefalitis de San Luis
huésped
- Virus de la encefalitis Japonesa
- Virus del rio Nilo Occidental
- Virus del Zika
30 nm Proteína prM/M
- Virus del dengue
Proteína precursora de membra
- Diámetro 50nm
Semanas a meses
>>> probabilidad de
Inmunidad cruzada: Temporal Inmunidad homologa: permanente dengue grave.
, Membrana viral
Proteoglicanos
Espacio intracelular, pH acido
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