Inhoud
1. Intro en algemene fysiologische begrippen ........................................................................................ 4
1.1 Homeostase .................................................................................................................................. 4
1.2 Feedback ....................................................................................................................................... 5
1.3 Medische oriëntatietermen .......................................................................................................... 6
1.4 Lichaamsholtes (Cavities) .............................................................................................................. 7
2. Weefsels in detail .............................................................................................................................. 10
2.1 De vier primaire weefsels: Epitheel ............................................................................................ 10
2.2 Het brein ..................................................................................................................................... 12
2.3 De vier primaire weefsels: Bindweefsel ...................................................................................... 13
2.4 De vier primaire weefsels: Spierweefsel ..................................................................................... 21
2.5 De vier primaire weefsels: Neuronaalweefsel ............................................................................ 21
3. Neurobiologie deel 1 ......................................................................................................................... 26
3.1 Het zenuwstelsel ......................................................................................................................... 26
3.2 Cel-cel communicatie CNS .......................................................................................................... 29
3.3 Rustmembraanpotentiaal ........................................................................................................... 31
3.4 Signaal overdracht en graded potentials .................................................................................... 33
3.5 Actiepotentiaal............................................................................................................................ 35
3.6 Summatie, integratie, divergentie en convergentie ................................................................... 36
4. Neurobiologie deel 2 ......................................................................................................................... 38
4.1 Het zenuwstelsel (integratie) ...................................................................................................... 38
4.2 Visuele informatieverwerking ..................................................................................................... 41
5. Neurobiologie deel 3 ......................................................................................................................... 49
5.1 Somatomotorisch systeem ......................................................................................................... 49
5.2 Autonoom (visceromotorisch) systeem ...................................................................................... 51
5.3 verschil in type neuronen en neurotransmitters in beide systemen.......................................... 52
5.4 Reflex en motoriek ...................................................................................................................... 54
6. Nieren en vloeistofregulatie ............................................................................................................. 59
6.1 Anatomische bouw en functie van de nieren ............................................................................. 59
5.2 Renale processen ........................................................................................................................ 61
5.3 Klaring ......................................................................................................................................... 65
5.4 Waterhuishouding ...................................................................................................................... 67
5.5 Het Renine-Angiotensine-Aldosteron Systeem (RAS) ................................................................. 72
7. Het endocriene systeem ................................................................................................................... 76
7.1 Classificatie hormonen................................................................................................................ 76
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7.2 Hormonen algemeen incl. interacties ......................................................................................... 78
7.3 Hypothalamus – Hypofyse systeem ............................................................................................ 79
7.4 Ziektebeelden: hypo- en hypersecretie ..................................................................................... 82
7.5 Hormonen van de bijnier ............................................................................................................ 83
8. Regulatie van metabolisme............................................................................................................... 87
8.1 Schildklier: anatomie & hormoonproductie ............................................................................... 87
8.2 De calciumbalans ........................................................................................................................ 90
8.3 Vitamine D & rol in calciumbalans .............................................................................................. 92
8.4 Regulatie van voedselopname .................................................................................................... 93
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1. Intro en algemene fysiologische begrippen
Fysiologie = De dynamische studie van in dit geval het lichaam.
Le milieu intérieur:
Het constant houden van het interne milieu is de voorwaarde voor een vrij en onafhankelijk leven.
Intern milieu: Extracellulaire vloeistof, bv. bloed
Extern milieu: Dat wat je omgeeft, de omgeving
Handhaving door: homeostase Grieks: ὅμοιος (homoios, "similar”) and στάσις (stasis, "standing still”)
1.1 Homeostase
Belang van homeostase:
• Het handhaven van het interne milieu van een organisme op een steady en gebalanceerd
niveau
• Doel: creëren van optimale condities voor het organisme en de cellen. Leerdoel:
Homeostase en de relatie met het goed functioneren van een organisme toe te lichten
Brain
Afferent:
Aanvoerend Efferent:
Uitvoerend
Voorbeelden van homeostase:
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