Summary
Samenvatting Diabetes
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Samenvatting van 9 pagina's voor het vak Pathologie aan de VIVES (Diabetes)
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Pathologie: DiabetesPancreas
Endocriene klieren → Productie hormoon; insuline + glucagon
Exocriene klieren → Afvoerweg sappen + enzymen
Eilandjes van langerhans:
- Alfacellen
- Bètacellen
→ Productie:
- Insuline
- Glucagon
1) Insuline:
- Sleutel glucose → spier- vetcellen binnen treden
- Hersen & levercellen, RBC geen insuline nodig
Te weinig → hyperglycemie
Teveel glucose in lichaam = GLYCOGEEN opgeslagen in spiercellen + lever
Andere suiker reserve = vetten
Glycogeen = Reserve → voorraad glucose
2) Glucagon:
- Levercellen breken glycogeen af → Glucose komt in bloed = verhogen glycemie
- Remmen Bètacellen van pancreas = aanmaak insuline dalen
Hypertoon glucose 20% - 30%
Gycogenese:
= Vorming glycogeen
→ Glucose door insuline omgezet in glycogeen
Glycogenolyse:
= Omzetting glycogeen in glucose → lever, spieren
Geactiveerd → glucagon
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