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Midterm Exam NR565 NR 565 Advanced Pharmacology Care $12.49   Add to cart

Exam (elaborations)

Midterm Exam NR565 NR 565 Advanced Pharmacology Care

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Midterm Exam: NR565/ NR 565 Advanced Pharmacology Care ASCVD Risk Score Ezetimibe Use Ezetimibe Lifestyle Changes for High Cholesterol Minimizing Side Effects Organic Nitrates Therapeutic Action Ranolazine Contraindications Statin Prescription Age CCB Role in Variant Angina HF Worsening S...

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  • March 2, 2024
  • 11
  • 2023/2024
  • Exam (elaborations)
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Midterm Exam: NR565/ NR 565 Advanced
Pharmacology Care

1). Ascvd risk score

 Ans: Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with
greater risk for those with diabetes and a risk score >7.5%


2). Ezetimibe use

 Ans: Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with
a statin or fibrate


3). Ezetimibe

 Ans: Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing
absorption from the small intestine, without affecting triglycerides


4). Lifestyle changes for high cholesterol

 Ans: Non-drug measures to lower LDL, including diet, exercise, weight control, and
smoking cessation


5). Minimizing side effects

 Ans: Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally
well-tolerated side effects


6). Organic nitrates therapeutic action

 Ans: Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels,
reduction of preload and afterload, and promotion of vasodilation




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, 7). Ranolazine contraindications

 Ans: Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes,
including grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal
drugs, and some CCB


8). Statin prescription age

 Ans: Avoid in children under 10


9). Ccb role in variant angina

 Ans: Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply


10). Hf worsening symptoms medication

 Ans: Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help
with symptoms


11). Ccb stable angina

 Ans: Promotes relaxation of peripheral arterioles, decreasing afterload and reducing
cardiac oxygen demand


12). Nitro patches side effect response

 Ans: Prescribe a BB to help with increased heart rate


13). Cyp450 inhibitors and reducers

 Ans: When not used correctly, they lead to increased side effects, adverse reactions,
and toxicity


14). Gouty arthritis treatment decision

 Ans: In patients with infrequent flareups (less than three per year), NSAIDs are the first
line agent for relieving pain




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