Midterm Exam NR565 NR 565 Advanced Pharmacology Care
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Course
NR 508
Institution
NR 508
Midterm Exam: NR565/ NR 565 Advanced Pharmacology Care
ASCVD Risk Score
Ezetimibe Use
Ezetimibe
Lifestyle Changes for High Cholesterol
Minimizing Side Effects
Organic Nitrates Therapeutic Action
Ranolazine Contraindications
Statin Prescription Age
CCB Role in Variant Angina
HF Worsening S...
Midterm Exam: NR565/ NR 565 Advanced
Pharmacology Care
1). Ascvd risk score
Ans: Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with
greater risk for those with diabetes and a risk score >7.5%
2). Ezetimibe use
Ans: Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with
a statin or fibrate
3). Ezetimibe
Ans: Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing
absorption from the small intestine, without affecting triglycerides
4). Lifestyle changes for high cholesterol
Ans: Non-drug measures to lower LDL, including diet, exercise, weight control, and
smoking cessation
5). Minimizing side effects
Ans: Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally
well-tolerated side effects
6). Organic nitrates therapeutic action
Ans: Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels,
reduction of preload and afterload, and promotion of vasodilation
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, 7). Ranolazine contraindications
Ans: Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes,
including grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal
drugs, and some CCB
Ans: Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help
with symptoms
11). Ccb stable angina
Ans: Promotes relaxation of peripheral arterioles, decreasing afterload and reducing
cardiac oxygen demand
12). Nitro patches side effect response
Ans: Prescribe a BB to help with increased heart rate
13). Cyp450 inhibitors and reducers
Ans: When not used correctly, they lead to increased side effects, adverse reactions,
and toxicity
14). Gouty arthritis treatment decision
Ans: In patients with infrequent flareups (less than three per year), NSAIDs are the first
line agent for relieving pain
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