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Samenvatting histologie van de orgaanstelsels: Lymfoïde organen, 2e bachelor biomedische wetenschappen $7.78   Add to cart

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Samenvatting histologie van de orgaanstelsels: Lymfoïde organen, 2e bachelor biomedische wetenschappen

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Samenvatting histologie van de orgaanstelsels: Lymfoïde organen 2e bachelor, 1e semester Biomedische wetenschappen

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  • March 18, 2024
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  • 2022/2023
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Histologie: Lymfoïde organen

Lymfoïde organen:

 Beenmerg
 Diffuus lymfoid weefsel
 Tonsillen
 Platen van Peyer
 MALT: GALT en BALT

Lymfeknoop

Basis opbouw:

Reticulair bindweefsel bestaande uit reticulumcellen en sterke vertakkingen ->
lymfocyten, macrofagen, neutrofielen ondersteunen netwerk

Boomvormig orgaan met bolle en holle zijde

 Bolle zijde: aanvoerende lymfevaten
 Lymfe komt in subcapsulaire sinus, zet zich voort langs
trabekels -> lymfe richting merg in mergsinussen en stroomt
langs plaatsen met mergstrengen -> lymfestroom vertraagt
 Holle zijde: 1 of 2 afvoerende lymfevaten, arterie treedt binnen en vene treedt buiten

Opdeling schors- en mergzone  paracorticale zone = overgang cortex-merg -> hoofdzakelijk T-
lymfocyten

 Schorszone (cortex): stapeling lymfefollikels -> hoefijzervormige structuren bestaande uit B-
lymfocyten
 Mergzone: mergstrengen en mergsinussen

Milt

Functies:

1. verdedigingsbarrière tegen micro-organismen
2. vorming rode bloedcellen
 embryonaal en bij myeloïde metaplasie (chronisch
bloedverlies/leukemie)
3. afbraak erythrocyten: macrofagen en strengen van Billroth
4. fagocytose + immunologische afweer
 fagocytose: macrofagen in strengen van Billroth
 plasmacellulaire reactie: humorale reactie in outer PALS, na t-cel activatie in inner
PALS
 follikelcentrumreactie
5. opslag van bloed (niet belangrijk bij mensen)

Rode pulpa:

 Strengen van Billroth: macrofagen, monocyten, lymfocyten, plasmacellen
 Veneuze sinussen

Witte pulpa:

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