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PACOP VIOLET- PCOL questions with correct answers
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PACOP VIOLET- PCOL questions with correct answers
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PACOP VIOLET- PCOL questions with correctanswers
A Correct Answer-Mechanism of action of local anesthetics.
A. Block sodium channel thereby stopping axonal conduction
B. Block alpha and beta receptor
C. Block neuronal firing by decreasing Ach in the neuromuscular junction
D. Inhibition of acetylcholinesterase enzyme
E. Inhibition of enzyme responsible for pain response
E Correct Answer-The following are factors that affect the absorption of drug from
the gastrointestinal(GI) track except.
A. Surface area of absorption
B. Blood flow to the site of absorption
C. Physical state of the drug
D. Concentration of the drug at the site of absorption
E. Protein binding
E Correct Answer-Continued stimulation of cells with agonists generally results in which of the following?
A. Desensitization
B. UP-regulation
C. Down-regulation
D. A and B E. A and C
A Correct Answer-Drug that lacks intrinsic efficacy but retains affinity and competes with the agonist for the binding sites of the receptor.
A. Competitive antagonist
B. Full agonist
C. Non-competitive antagonist
D. Partial antagonist
E. Partial agonist
C Correct Answer-This type of drug produce its effect by binding a site on the receptor distinct from that of the primary agonist and thereby changing the affinity of the receptor for the agonist.
A. Competitive antagonist
B. Full agonist
C. Non-competitive antagonist
D. Partial antagonist
E. Partial agonist
B Correct Answer-In this type of study, participants are blinded to treatment assignment, investigators are not.
A. Double-blind study
B. Single-blind study
C. Masking D. Open-label
E. Un-blinded study
C Correct Answer-The neurotransmitter of all preganglionic autonomic fibers, and all postganglionic parasympathetic fibers.
A. Norepinephrine
B. Noradrenaline
C. Acetylcholine
D. A and B
E. A and C
B Correct Answer-The release of Ach and other neurotransmitters by exocytosis is inhibited by:
A. Acetylcholinesterase
B. Botulinum toxin
C. Reserpine
D. Me tyrosine
E. Guanethidine
E Correct Answer-All of the following are enzymes involved in the biosynthesis of
epinephrine from tyrosine EXCEPT:
A. Tyrosine hydroxylase
B. Aromatic L amino acid decarboxylase
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