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Pcol Exam 2 Drugs questions with complete solutions
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Pcol Exam 2 Drugs questions with complete solutions
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Pcol Exam 2 Drugs questions with complete solutionsWhat is a common ending of phentiathazine derivatives? Correct Answer--azine
Describe phenothiazines. Correct Answer-Blocks D2>5-HT2a
High EPS
May have antiemetic effects
butyriphenone Correct Answer-Haloperidol+
Blocks D2>5-HT2a
High EPS
clozapine Correct Answer-atypical antipsychotic
Very low EPS
5HT2a> D2(highest affinity D4)
Suppress TD
Reduce + and - symptoms
Agranulocytosis
risperidone Correct Answer-atypical antipsychotic
5HT2a>D2
No blood toxicity
olanzapine Correct Answer-atypical antipsychotic
Very low EPS
5HT2a>D2 Reduce + and - symptoms
Weight gain and metabolic disorders
quetiapine Correct Answer-atypical antipsychotic
Very low EPS
D2>5HT2a
Less weight gain tendency
Reduce + and -
ziprasidone Correct Answer-atypical antipsychotic
Very low EPS
Injectable acute treatment
May cause serious cardiac arrhythmias
5HT2a>D2
aripiprazole Correct Answer-atypical antipsychotic
Very low EPS
Most widely prescribed
Partial agonist at D2 receptors
High affinity, binds rather than DA at D2 receptors
asenapine Correct Answer-atypical antipsychotic
Low EPS
Acute manic episodes too
Sublingual administration
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