ASCP MLS CERTIFICATION EXAM 2024 QUESTIONS AND DETAILED ANSWERS WITH RATIONALE S| GUARANTEED PASS Which of the following condition is the most common cause of increase anion gap? A.Metabolic alkalosis B. Metabolic acidosis Respiratory acidosis Respiratory alkalosis Correct Answer B. Metabolic acidosis Rationale: High anion gap metabolic acidosis is caused generally by the body producing too much acid or not producing enough bicarbonate. This is often due to an increase in lactic acid or ketoacids, or it m ay be a sign of kidney failure. More rarely, high anion gap metabolic acidosis may be caused by ingesting methanol or overdosing on aspirin. Which of the following enzymes has the longest elevation after Myocardial Infarction (MI)? CK-MB Myoglobin Troponin AOTA Correct Answer C. Troponin Rationale: Troponin is elevated up to 10 -14 days after Myocardial Infarction. Specific gravity measured by refractometer: 1.035. Protein and glucose both trace in reagent strip: Presence X -ray medium Albuminuria Glucosuria Normal Correct Answer A. Presence X -Ray medium Rationa le: Xray medium/Radiographic dye can cause erroneo us results in urine specific gravity measurement. A patient with walking pneumonia is being treated with penicillin. State one possible condition why the patient is not recovering: The organism produces beta lactamase The organism has no cell wall The organism has capsule The organism produces an enzyme that neutralizes the antibiotic Correct Answer B. The organism has no cell wall. Feedback Pneumonia caused by Mycoplasma pneumoniae is routinely treated with antibiotics, although the disease is u sually self-limiting. The disease is treated with macrolide, tetracycline, or fluoroquinolone classes of antibiotics. All mycoplasmas lack a cell wall and, therefore, all are inherently resistant to beta -lactam antibiotics (e.g., penicillin). What is the coefficient of variation if the mean is 90 and the standard deviation is 5.48? 2.75 6.09 5.68 30 Correct Answer B. 6.09 Feedback: CV= SD/meanX100, (5.48/90)X100= 6.09. Blood smear below denotes Hairy Cell Leukemia (HCL), which of the following test is used to identify this type of leukemia? Image. 1 Myeloperoxidase Tartrate -resistant acid phosphatase Tartrate -resistant alkaline phosphatase Sudan Black Correct Answ er B. Tartrate -resistant acid phosphatase Feedback: Hairy cells demonstrate strong positivity for tartrate -resistant acid phosphatase (TRAP) staining. The hairy cells are larger than normal and positive for CD19, CD20, CD22, CD11c, CD25, CD103, and FMC7. Use to differentiate Salmonella from Citrobacter: Lysine decarboxylase ONPG Indole Vogues Proskauerterm -9 Correct Answer A. Lysine decarboxylase Feedback: Salmonella (+); Citrobacter ( -) Arrange the common Rh antigens according to immunogenicity (greatest to least): D>c>E>C>e D>C>E>c>e D>c>E>e>C C>D>c>E>e Correct Answer A. D>c>E>C>e Feedback Most immunogenic D > c > E > C > e least immunogenic. Most common error in Polymerase Cha in Reaction (PCR) is NUCLEIC ACID CONTAMINATION. A True (Correct Answer) B False Correct Answer A. True What disease is associated with the possession of HLA -B27? Ankylosing spondylitis
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