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Pxt-Safety-And-Prognosis-Usmle-Step-3-Preparation-Resources.docx
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1-What is the long term prognosis in Pt with Kawasaki who develops Coronaryartery Stenosis ? ANS- Risk for future heart conditions
2-Prognosis of pt with Kawasaki who wasnt treated ?Ans: increased likelihood of
developing coronary artery aneurysm in 10 days
3-Long term prognosis of women on HRT? Ans: Breast cancer in 5 years
4- New born with Thalasemia major treated with hyperstransfusion prognosis?
Ans: couple of years survival with organ damage from Iron overload
5-Prognosis of Pulmonary Sarcoidosis? Ans: symptomatic Pxts or pxts with
impaired PFTs usually receive 12 - 24 months of oral Glucocorticoids. Most (75%)
resolve over time and do not recur.
6-Prognosis of patients with late life depression (age >65) ? Ans: Increased risk of
developing Alzhimers and all forms of dementia
7-Worst prognosis of Sarcoidosis is seen in these pxts? Ans: Pxts age > 40, african
american or those with progressive pulmonary fibrosis or extraocular
manifestations such as cardiac or neurologic have worse outcomes
Cor pulmonale and nephrocalcinosis reflected the poorest prognosis while lupus
pernio and sarcoidosis of the mucosa of the upper respiratory tract rarely
resolved. Bone sarcoidosis also implied chronicity but in four of 31 patients there
was no clinical evidence of disease activity two years after the initial diagnosis,
although naturally the bone radiograph was still abnormal. Hepatomegaly carried
a worse prognosis than splenomegaly, or indeed, than the finding of pulmonary
mottling without hilar glands--a stage three chest radiog ( pub med)
8-Prognosis of patients with Behavioral variant Fronto-temporal dementia ? Ans:
Typically fatal within 8 years of disease onset
9-Prognosis of Parvovirus B19? Ans: There is no long term sequelae and the
condition is usually self limited.
10- What is the prognosis of essential tremor? Ans: The tremor in pxts with
benign or familial features gets worsen with time and can cause difficulty in the
,performance of fine motor tasks. Also pxts can have normal life expectancy
without any significant disability.
11- what are favorable prognostic factor in schizophrenia?
Ans: female, older age at onset >40 yr old, acute onset of sx no prodorme,
predominant positive sx (rather than negative sx) ,presence of mood sx, good
pre0morbid functioning, identifiable precipitant , no fam-hx of
schizophrenia ,good family support, shorter duration of active sx.
12- What is the prognosis of late lyme arthritis in young children ?
Ans: lyme arthritis can be treated successfully with a 28-day course of oral
amoxicillin or doxycycline. Most patients are disease-free within 6-12 months.
13- Prognosis of ADPKD - most develop progressive renal insufficiency as they
age, approximately 50% require renal replacement therapy by age 60. (Uworld
ID: 5961)
14- What is the prognosis of untreated progressive
multifocalleukoencephalopathy in HIV patient?
Ans: Without treatment with highly active antiretroviral therapy (HAART), the
majority of patients stricken with progressive multifocalleukoencephalopathy will
die within 3-6 months of symptom onset. Usage of HAART in this patient
population may prolong survival for more than two years.
14: What is the prognosis of lyme in pregnancy?
Ans: There is little to no risk to the fetus if the mother contracts Lyme disease
during pregnancy if it is appropriately treated. ( tx during pregnancy is
amoxicillin or cefuroxime)
15: ARDS
, Long-term sequelae (neurocognitive deficits, impaired muscle strength and lung
function, psychiatric illness) are common following recovery from ARDS
16. Compartment syndrome prognosis (uworld ID: 10149) : Time to intervention
is the most important factor predicting complete functional recovery of the limb.
17. Hand Food Mouth Disease (uw)
Oral and skin lesions typically self-resolve within a week
Handwashing is important; still contagious for several weeks after rash
resolution
18. Asthma (MTB 3)
Respiratory Acidosis with CO2 retention -> ICU; also indication for intubation
and ventilation
In Asthma, it should be respiratory alkalosis if there’s hyperventilation; any
decrease in pH or CO2 >40 à ICU
19. Onychomycosis (UW)
Advice patient about risks of treatment (hepatotoxicity) and potential of
treatment failure and recurrence
20. Asymptomatic bacteriuria
Common in women as they age (prevlance >20% in women of age >80)
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