MIP 342 Pro Final Exam Questions With All Complete Solutions 2024

What makes the mucosal immune system unique? - correct answer Dimorphic IgA. Default state is immunosuppressive. Memory T cells alway present. The Hygiene hypothesis asserts that - correct answer all of the above Autoimmunity or increased extracellular bacterial infections can be caused by - correct answer b. Complement deficiencies Which is not a mechanism by which tumors escape immune recognition - correct answer b. Affinity Maturation Which is the most likely sequence of events of a typical mucosal immune response to an extracellular bacterial pathogen - correct answer A. Bacteria that escape physical barriers, AMPs and IgA are phagocytosed by M cells or TEDs from macrophages or DCs, which travel to mesenteric lymph nodes, process and present pathogen peptide antigens via MHC II molecules to B and T cells, which become activated and travel back to the mucosa via integrin receptors and eliminate the pathogen. A type II (cytotoxic) hypersensitivity reaction is - correct answer e. stimulated by cell surface receptors, mediated by IgG and results in altered cell signaling and autoimmunity What are distinctive features of the mucosal immune system? - correct answer Associated with mucosal epithelia. Unique lymphoid tissue like Peyer's patches. Special antigen uptake mechanisms like M cells in Peyer's patches. What are M cells/what are some of their unique features? - correct answer M cell = Microfold cell. Antigen uptake cell associated with Peyer's patches. Peyer's patches are connected directly to lymph nodes to the antigens can be taken there quickly. Sample pathogens.