NURS 5334-PHARM: Antimicrobials part 1/ Module 2 UTA 35 CORRECTLY ANSWERED QUESTIONS LATEST UPDATE
Drug resistant bacteria (seven listed)
Four basic actions of bacterial drug resistance
Spontaneous mutation
Conjugation in bacteria
Nosocomial infections
Superinfection
Public Health Action Pla...
2). Four basic actions of bacterial drug resistance
Ans: •Decrease the concentration of a drug at its site of action
•Inactivate a drug
•Alter the structure of
drug target molecules
•Produce a drug antagonist
3). Spontaneous mutation
Ans: •Random changes in a microbe's DNA
•Resistance to one drug
4). Conjugation in bacteria
Ans: •Extrachromosomal DNA is transferred from one bacterium to another
•Gram-negative bacteria
•Multiple drug resistance
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, 5). Nosocomial infections
Ans: •Health care-associated infections (HAI)
6). Superinfection
Ans: •New infection that appears during the course of treatment for a primary infection
•Because superinfections are caused by drug-resistant microbes, they often are difficult to
treat
7). Public health action plan to combat antimicrobial resistance
Ans: •Focus Area I: Surveillance
•Focus Area II: Prevention and Control
•Focus Area III: Research
•Focus Area IV: Product Development
8). Penicillin moa
Ans: •Weaken the cell wall, causing bacteria to take up excessive water and rupture
•Active only against bacteria undergoing growth and division
•Bactericidal
-beta-lactam family
*Give macrolides when pt is allergic to PCN
9). Three factors to bacterial resistance to pcns
Ans: •Inability of penicillins to reach their targets
•Inactivation of penicillins by bacterial enzymes
•Production of penicillin-binding proteins (PBPs) that have a low affinity for penicillins
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