Summary Cell and Molecular Biology - Cell and molecular biology 102 (Amb102)
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Course
Cell and molecular biology 102 (AMB102)
Institution
University Of Sargodha
Book
Cell and Molecular Biology
I made the summary of replication from karp cell and molecular biology these notes help me to pass my exam as well as it help me to understand all the diagrams
Test Bank for Cell and Molecular Biology Concepts and Experiments, 8th Edition by Karp | Complete Elaborated and Latest Test Bank. ALL Chapters included and updated | Graded A+
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Test Bank for Cell and Molecular Biology Concepts and Experiments 8th Edition Karp | Complete A ll Chapters 2024/2025
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Cell and molecular biology 102 (AMB102)
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DNA REPLICATION
, DEFINITION
• DNA replication is an enzymatic polymerization reactio
which DNA strand is used as a template to synthesize a c
with a base sequence that is complementary to the temp
Replication is semi conservative; each parent single stran
present in one of the double-stranded progeny molecules
, The original Watson-Crick proposal f
• The proposal for the structure of DNA replication of a double-helical molecu
by Watson and Crick in 1953 was
accompanied by a suggested
mechanism for its “self-duplication.”
• The two strands of the double helix are
held together by hydrogen bonds
between the bases.
• Individually, these hydrogen bonds
are weak and readily broken.
• Watson and Crick envisioned that
replication occurred by gradual
separation of the strands of the double
helix, much like the separation of two
halves of a zipper.
, • Semiconservative replication
• Because the two strands are
complementary to each other, each
strand contains the information
required for construction of the other
strand.
• Thus once the strands are
separated, each can act as a
template to direct the synthesis of
the complementary strand and
restore the double-stranded state.
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