ALU 301 Final Exam Review 2024 Cells that can recognize altered surface molecules on mutated host cells as "foreign" and move to destroy the cell that carries them are: 1. Complements 2. Receptors 3. Natural Killers 4. Mediators - ANSWER Natural Killers All of the following are common examples of autoimmune disease EXCEPT: 1. Hashimoto's thyroiditis 2. Rheumatoid arthritis 3. Graves' Thyroid Disease 4. Poliomyelitis - ANSWER Poliomyelitis Which of the following statements regarding serum immunoglobulin levels is/are correct? A. Monoclonal gammopathy is a risk for transformation into multiple myeloma. B. Polyclonal gammopathy is frequently associated with chronic infections. C. Low serum globulin can indicate a primary immune deficiency. 1. A only 2. B o nly 3. A and C only 4. All of the above - ANSWER All of the above The type of immune cell that differentiates in the bone marrow is: 1. T-lymphocyte 2. Helper T-cells 3. Natural Killer cells 4. B-lymphocyte - ANSWER B-lymphocyte Which of the following statements regarding T-lymphocytes is/are correct: A. One type is cytotoxic T-cells B. They eliminate infected cells C. They provide immunity by production of antibodies 1. A only 2. A and B only 3. B and C only 4. All of the above - ANSWER A and B The cells of the immune system originate in the: 1. spleen 2. white blood cells 3. bone marrow 4. lymph nodes - ANSWER bone marrow A polyclonal gammopathy pattern on serum protein electrophoresis (SPEP) can indicate all of the following EXCEPT: 1. Multiple myeloma 2. Infectious mononucleosis 3. Chronic hepatitis 4. Connective tissue disease - ANSWER Multiple Myeloma Which of the following statements regarding common variable immunodeficiency is/are correct? A. It is a congenital disease. B. Diarrhea is a recurring problem C. Adults usually present with chronic sinus infections. 1. A only 2. B only 3. A and C only 4. B and C only - ANSWER B and C Functions of T-Lymphocytes include which of the following? A. defense against cancer B. elimination of infected cells C. correction of errors in DNA 1. A and B only 2. A and C only 3. B and C only 4. All of the above - ANSWER A and B Which of the following is an autoimmune disease: A. Systemic lupus B. Idiopathic thrombocytopenia C. Hashimoto's thyroiditis 1. A only 2. A and B 3. B and C 4. All of the above - ANSWER All of the above All of the following about the Innate system are true EXCEPT: 1. It changes over the lifetime of an individual 2. It is very broad in ability to respond to invasive organisms 3. Response is non-specific 4. Has no immunological memory - ANSWER It changes over the lifetime of an individual Which of the following are components of the Innate system? A. Physical barrier B. Red Blood Cells C. White Blood Cells 1. A only 2. A and C 3. B and C - ANSWER A and C The most abundant white blood cells in the blood count differential are: 1. Monocytes
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