PHA 3112 Midterm 1 latest complete update A+ graded
Drugs include (4) - prescription and non-prescription
- biologically-derived products (biologics)
-disinfectants
-natural health products
biologically-derived products (biologics) - often made in the lab (biotechnology)
...
Drugs include (4) - prescription and non-prescription
- biologically-derived products (biologics)
-disinfectants
-natural health products
biologically-derived products (biologics) - often made in the lab (biotechnology)
-come from living organisms or their cells
- used to treat diseases and medical conditions including anemia, diabetes, inflammatory bowel
disease, psoriasis, rheumatoid arthritis, hormone deficiency and some forms of cancer
biologics include (5) - blood and blood products
- monoclonal antibodies
-cell, tissues and organs, including xenografts
- gene therapies
-viral and bacterial vaccines
chemical name Describes the drug's chemical composition and molecular structure
generic name or INN legal noncommercial name for a drug
brand name name or company the drug is sold as
what happens when a drug enters the body? 1. drug is administered
2. drug goes into solution
3. absorption from digestive tract into the systemic circulation
4. reversible binging to plasma proteins and circulation/distribution in the body
5. action (bind to specific receptors)
6. transformation/metabolism (by liver)
- all processes influence the speed of onset and duration of drug effects
metabolites substances produced when the body breaks down a drug
can be active or inactive
, pharmacokinetics study of the factors determining concentration of drug at the receptor site,
as a function of time and dose administered
- ADME
what the body does to the drug
ADMEabsorption
distribution
metabolism
excretion
Pharmacodynamics study of the biochemical and physiological mechanisms by which drugs
produce their effects (includes mechanism of action)
what the drug does to the body
a.c before meals
ad lib as much as desired/free choice
b.i.d twice a day
h.s bedtime
IM intramuscular
IV intravenous (into the vein)
OTC over the counter
p.c after meals
p.o by mouth, orally
p.r rectally
p.r.n as needed
p.v. vaginally
q every, per
q.d every day
q.h.s every day at bedtime
q.i.d 4 times a day
SC, SQ, subQ subcutaneous
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