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Nursing Pharmacology Study Guide Questions and Correct Answers

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Nursing Pharmacology Study Guide Questions and Correct Answers Absorption Affinity blood-brain barrier diffusion distribution drug-protein complexes enterohepatic recirculation enzyme induction excretion first-pass effect fetal-placental barrier hepatic microsomal enzyme system isozyme...

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  • April 10, 2024
  • 12
  • 2023/2024
  • Exam (elaborations)
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Nursing Pharmacology Study Guide Questions
and Correct Answers

1). Absorption

 Ans: the process by which drug molecules move from their site of administration to the
blood


2). Affinity

 Ans: the ability of some tissues to attract, accumulate and store drugs in high
concentrations relative to other tissues


3). Blood-brain barrier

 Ans: Blood vessels (capillaries) that selectively let certain substances enter the brain
tissue and keep other substances out


4). Diffusion

 Ans: process by which molecules tend to move from an area where they are more
concentrated to an area where they are less concentrated


5). Distribution

 Ans: the transport of drugs throughout the body after they are absorbed


6). Drug-protein complexes

 Ans: formed when a drugh that binds reversibly to a plasma protein, particularly
albumin, that makes the drug unavailable for distribution to its site of action


7). Enterohepatic recirculation

 Ans: recycling of drugs and other substances by the circulation of bile through the
intestine and liver




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, 8). Enzyme induction

 Ans: process by whick a drug increases the activity of the hepatic microsomal
enzymes


9). Excretion

 Ans: the process of removing substances from the body


10). First-pass effect

 Ans: mechanism whereby drugs are absorbed enter into the hepatic portal circulation
and are inactivated by the liver before they reach the general circulation


11). Fetal-placental barrier

 Ans: special anatomic barrier that inhibits many chemicals and drugs from entering the
fetus


12). Hepatic microsomal enzyme system

 Ans: as it relates to phamacotherapy, liver enzymes that metabolize drugs as well as
nutrients and other endogenous substances, sometimes called the P-450 System


13). Isozymes

 Ans: multiple similar forms of an enzyme that perform slightly different metabolic
functions


14). Loading dose

 Ans: relatively large dose of a drug given at the beginning of treatment to rapidly obtain
a therapeutic response


15). Maintenance doses

 Ans: amount of drug that keeps the plasma drug concentration in the therapeutic range


16). Metabolism




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