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Samenvatting Schema diuretica

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Schema alle besproken diuretica.

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  • January 23, 2019
  • 3
  • 2017/2018
  • Summary

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By: daisykadesa • 4 year ago

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By: alanfeyaerts • 5 year ago

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DIURETICA
KOOLZUURANHYDRASE THIAZIDEN LISDIURETICA K+-SPARENDE DIURETICA OSMOTISCHE
INHIBITOREN DIURETICA
Absorptie Goed na perorale inname ENKEL PER OS Snel bij orale inname Ive toediening
Eliminatie Renale excrete Secrete via mechanisme voor Door glomerulaire Inactvate in de lever Glomerulaire filtrate
organische zuren: compette filtrate en secrete
met urinezuur
Indicatie Niet meer als diuretca - 1e lijns bij hypertensie (ook - onderhoud hartalen SPIRONOLACTONE - bij een gedaald
- openhoek glaucoom zwak vasodilaterend) - acuut longoedeem (IV) - overmaat mineralocort. urinevolume
- alkaliniseren urine - onderhoud bij congestee HF - nierziekten (hoge dosis) (prim. + sec. hyperaldo) - verhoogde
- metabole alkalose door - neerolithiase door - levercirrose - lage dosis gunstg bij HF intracraniile
diuretcagebruik bij patint met hypercalciurie (calciurie daalt - hypercalciimie (samen - resistente essentile (hersenoedeem) en
zware hartdecompensate door inname thiaziden) met zoutneuus) hypertensie intraoculaire
- mountain sickness - neerogene diabetes insipidus - hyperkaliimie ALS DIURETICA (glaucoom) druk
(PARADOXAAL EFFECT) - combi met K+-verliezende - bij acute
diuretca tubulusnecrose
Bijwerkinge - verergeren metabole oe - hypokaliimische metabole - hypokaliimische - hyperkaliimie (opgelet bij - natriurese < diurese,
n respiratoire acidose alkalose metabole alkalose nierlijden en combi met β- waardoor risico op
- nierstenen - hyperuricemie + uitlokken - hypomagnesiimie (want blokkers, NSAIDs, ACE-inh.) hypernatriimie
- verlies K+ via de nier van jicht betere excrete divalente - gynaecomaste, impotente - transiinte expansie
- meer NH3 in de - hyperglycemie katonen) bij aldo-antagonisten van het extracellulair
systeemcirculate: gestegen - transiinte hyperlipidemie - dehydratate - metabole acidose volume waardoor HF
kans encephalopathie - hyponatriimie (ADH stjgt) - hyponatriimie - nierstenen verergert en oedemen
- overgevoeligheid - overgevoeligheid - hyperuricemie+ worden uitgelokt
(suleonamiden) (suleonamiden) uitlokken jicht - dehydratate en
- sedate bij hoge dosis - sedate - overgevoeligheid hypernatriimie door
- erectele dyseuncte (suleonamiden) verlies van vrij H2O
- ototoxiciteit
CI - door de renale excrete is - acuut longoedeem - K+-supplementen tegelijk - bij twijeel over
dosisaanpassing nodig bij - geen CI bij DM enkel in lage - neeropathie niereuncte
nierinsufficiinte dosissen toedienen) - gebruik NSAIDs oe ACE- - hartalen
inhib., sartanen, renine


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