Summary
Samenvatting Schema anticoagulantia
- Course
- Institution
Schema alle besproken anticoagulantia.
[Show more]
2 reviews
By: daisykadesa • 4 year ago
By: alanfeyaerts • 5 year ago
Seller
Follow
ciefarma2019
Reviews received
Content preview
ANTICOAGULANTIAVITAMINE K ANTAGONISTEN DIRECTE ORALE INJECTEERBARE ANTICOAGULANTIA
(VKA) ANTICOAGULANTIA (DOAC) (LMWHs)
Absorptie Hoog na perorale toediening Niet peroraal (iv of sc)
Eiwitbinding Hoog
Eliminatie Metabolisate in de lever
PK Werking houdt nog 3-4 dagen aan Ogenblikkelijke werking, maar eindigt ook snel
Lage T1/2
Indicaties - (samen met hoge dosis heparine) - primaire prevente veneuze thrombo- - veneuze thrombose (prevente DVT in
prevente uitbreiding diepe thrombose en embolie geïmmobiliseerde patint en murale thrombose na
ontstaan longembolen - thrombo-embolische prevente bij VKF MI)
- prevente thrombose patinten met - behandeling DVT en secundaire
mitraalstenose, langdurige VKF, prevente
kunstkleppen, recurrente DVT - prevente thrombose, langdurige VKF,
kunstkleppen, recurrente DVT
ENKEL INDIEN GEEN KLEPLETSELS
Interacties Heel veel, met GM met invloed op: - CYP3A4 en/of Pgp
- opname of metabolisme van het - voorzichtgheid met ant-aggreganta en
coumarine of vitK NSAIDs omwille van het verhoogd
- synthese, functe en klaring van elke bloedingsrisico
factor of cel met een rol in de hemostase
of fbrinolyse
- de integriteit van het epitheel
Bijwerkingen - bloedingsrisico (vooral GI) - bloedingsrisico - spontane bloedingen (indien dit gebeurt:
- teratogeniciteit - EVALUATIE INR en nier- en leverfuncte is toediening stoppen of protaminesulfaat toevoegen
- moeilijk om juiste plasmaconcentrate te noodzakelijk die inactef complex vormt met heparine)
verkrijgen door de trage werking en de - transiinte of ernstge thrombocytopenie
lange werkingsduur. (te laag: - mogelijks osteoporose bij langdurig gebruik
stollingsgevaar; te hoog: bloedingsrisico)
PT (INR) van patint moet regelmatg
bekeken worden
CI - zwangerschap (want gaat door placenta) - patinten ouder dan 75 jaar: lagere dosis
WM Competteve antagonisten van vitK. - directe selecteve orale factor Xa - (Unfractonated) Heparine bindt aan
1
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller ciefarma2019. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $4.88. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
79202 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now