True or False: Children metabolize drugs
faster than adults. - ANSWER-True
which are easier to excrete: water soluble
drugs or lipid soluble drugs? - ANSWER-
Water soluble
,What are the cytochrome p450 inducers?
(CRAPGPS) - ANSWER-Carbamazapine
Rifampin
Alcohol
Phenytoin
Griseofulvin
Phenobarbital
Sulfonylureas
and St. Johns Wort
what do CYP450 inducers do? - ANSWER-
increase metabolism of drug, reduces drug
level
,What are some examples of schedule 1
drugs? - ANSWER-heroin, LSD, marijuana
What are some examples of schedule 2
drugs? - ANSWER-amphetamines, some
opioids (morphine, meperidine, codeine)
dronabinol, short-acting barbiturates
what are some examples of schedule 3
drugs? - ANSWER--Tylenol (acetaminophen)
with codeine
-Hydrocodone with acteaminophen
(Vicodin, Loset, Lortab, Norco)
-Various other codeine preparations (less
than or equal to 1.8%)
-Buprenorphine (Buprenex, Subutex,
Suboxone)
, What are some examples of schedule 4
drugs? - ANSWER-Benzodiazepine
anxiolytics, muscle relaxers, and sedatives,
pentazocine, ambien, klonipine
What are some examples of schedule 5
drugs? - ANSWER-antidiarrheal, codeine
used as antitussives, loperamide, lyrica,
robitussin
what is the first pass effect? - ANSWER-
drugs absorbed from the GI tract enter the
portal vein and pass through the liver
before entering circulation.
decreases bioavailability
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