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ASCP BLOOD BANK EXAM WITH VERIFIED SOLUTIONS RATED A
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ASCP BLOOD BANK EXAM WITH VERIFIED SOLUTIONS RATED A
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ASCP BLOOD BANK EXAM WITH VERIFIED SOLUTIONS RATED A Define dosage CORRECT -Dosage is defined as an antibody reacting stronger with homozygous cells (such as KK) than with heterozygous cells (Kk) List the antigens that commonly show dosage? CORRECT -Kell. M. N. S, little s. F.y.a, F.y.b J.k.a, J.k.b. Antigens of the Rh system. Is the Duffy antigens F.y.a and F.y.b more prevalent in African Americans or in whites? CORRECT -In African Americans. 70% African Americans and it is very rare in whites. What does the term heterozygous mean? CORRECT -A diploid organism is heterozygous at a gene locus when its cells contain two different alleles of a gene. The cell or organism is called a heterozygote specifically for the allele in question, and therefo re, heterozygosity refers to a specific genotype. What distinguishes A1 from A2 blood groups? CORRECT -An A2 person may form anti -A1, but an A1 person will not form anti -A1. What is the only A.B.O phenotype that is incompatible with O cells. CORRECT -Bombay. The red cells of Bombay show a negative reaction to anti -H because the cells contain no H substance. A Bombay individual has a phenotype little hh and will type as group O. What antibodies are formed by an Bombay individual? CORRECT -Anti-A, Anti -B, Anti -H. Because a Bombay individual has three antibodies, the only compatible blood must be from another Bombay donor. Acquired B antigens have been found in what type of person? CORRECT -
A-persons. Is Acquired B phenotype a transient condition? CORRECT -Yes, Over time, when the root cause of the bacterial enzyme removal of the acetyl group is resolved, a patient's blood type will no longer show an acquired B antigen. What causes Acquired B phenotype. CORRECT -Acquired B occurs when the RBCs from a blood group A patient come in contact with bacterial enzymes known as "deacetylases" carried by bacteria that live in the colon - typically gram -negative rods. What is Acquired B usually associated with? CORRECT -colorectal malignancy, gastrointestinal obstruction, or gram -negative sepsis -where those bacteria can contact the RBCs. What does a strong reaction in reverse grouping suggest when it doesn't match the forward grouping? CORRECT -That the discrepancy is in forward grouping. What should be done if a strong reaction is seen in the reverse that doesn't match the forward? CORRECT -Incubate washed red cells at room temperature with anti -A and anti -A,B which will enhance reactions. What typing results are most likely to occur when a patient has an acquired B antigen? CORRECT -Anti-A-4+ Anti-B-1+ A1 cells -negative B cells -4+ Which blood group has the least amount of H antigen? CORRECT -A1B. This is due to both A and B epitope present on red cells compromising the availability of H epitope. A1B cells will yield weak reactions with anti H lectin. What type RBC's can be transfused to an A2 person with anti -A1? CORRECT -A or O because A1 is typically only reactive at room temperature. What might the forward and reverse type look like in a patient with a cold autoantibody? CORRECT -Forward and reverse A.B.O results as well as the auto control would be positive.
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