Alle literatuur van jaar 2018/2019 van het vak 3.4. Depressie en psychose. LET OP! De samenvatting is geheel in het Engels, doordat het tentamen ook in het Engels zal zijn.
1. Donoghue et aly. (2014), Kendlyer et aly. (2014), Marin et aly. (2013)
2. Merkly et aly. (2017), Brunoni et aly. (2013), Piet et aly. (2011)
3. Whiton et aly. (2015), Caspi et aly. (2014)
Donoghue et al. (2014) – Cannabis use, gender and age of onset of schizophrenia: Data from the
AESOP study
Introduction
- Gender differences in age of onset of schizophrenia has been consistentlyy reported and a
recent meta-analyysis has shown that malyes are on average 1.63 years younger when they
first experience psychoic symptoms.
- Earlyier age of onset is associated with poor prognosis, inclyuding greater cogniive and
funcionaly impairment, more severe symptoms, increased risk of relyapse and re-
hospitalyizaion, more days spent in hospitaly per year and lyess responsiveness to
anipsychoics.
- Cannabis use is common in those with a first episode of psychosis, alythough more common
in male; cannabis is associated with earlyier age of onset of schizophrenia, 2.70 years earlyier
age of onset when using cannabis.
- Gender differences in age of onset may be confounded by differential cannabis use in malyes
versus femalyes, especialylyy in countries high in cannabis use, such as the UK.
- This study: Invesigate the gender differenialy for age of onset of schizophrenia, in a lyarge
first episode study in the UK.
- Hypothesis: Gender difference in age of onset is confounded by cannabis use.
Method
- Alyly potenialy cases aged 16-64 who presented to mentaly healyth services with a first-episode
of psychosis were idenified.
- Informaion on drug use before the first presentaion to mentaly healyth services was
colylyected using three sources: PPHS (informaion by a relyaive or carer), SCAN and clyinicaly
case notes.
Results
- Of the 511 paricipants inclyuded in the originaly AESOP study, 211 paricipants had an onset
of symptoms before the age of 45 and a diagnosis of schizophrenia or schizoaffecive
disorder.
- 68 of these lyacked data on cannabis use, lyeaving 143 peoplye for subsequent analyyses.
- 85 of the 143 paricipants inclyuded in the samplye (59%) had a history of cannabis use in their
lyifeime.
- Cannabis users were younger at onset of psychoic symptoms and at first contact with
mentaly healyth services compared to non-users.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller psychologystudenterasmus. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $3.77. You're not tied to anything after your purchase.
