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Samenvatting - Circulatie en vasculaire stoornissen

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Een overzichtelijk en duidelijke samenvatting over het vak 'Circulatie en vasculaire stoornissen' (B3.2), geschreven door een derdejaars geneeskunde student aan de Vrije Universiteit van Amsterdam. Deze samenvatting is een combinatie van colleges, practica en oefententamens. Hierdoor is het gemakke...

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  • April 30, 2024
  • 62
  • 2023/2024
  • Summary
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EVS AANTEKENINGEN
College vaatwand pathologie 1 11




Atherosclerose en ingeammatie vaatwand
1
macrophage accumulation
2 formation of necrotic core
3 fibrous cap formation

,Endotheelfunctie
Regulering van

W weerstand doorbloeding volume
A angiogenese arteriogenese
B barriere functie
1 infiltratie ontstekingscellen
T thrombose homeostase




Bloeddruk
hartminuutvolume vaatweerstand

,Nitric Oxide Synthases
NOS 1 neuronaal NOS
Activiteit calcium afhankelijk
Neurotransmitter
NOS 11 induceerbaar NOS
Activiteit calcium onafhankelijk regulatie via genexpressie
expressie in o a macrofagen
Belangrijk bij immuunreacties tegen bacteriën
NOS 111 endotheel NOS
calcium afhankelijk
0 a geactiveerd door stromend bloed schuifkracht shear
reguleert doorbloeding trombose ontsteking
ADMA asymmetrisch DimethylArginine
DDAH breekt ADMA af

, Angiogenese arteriogenese
Angiogenese vorming nieuwe bloedvaten vanuit bestaande bloedvaten




arteriogenese toename diameter van bestaande arteriële bloedvaten




Adenosine parasympathisia
vasodilaterend effect op de bloedvaten actieve weefsels

wanneer cellen actief zijn metabolisch actief zijn neemt adenosine toe


Noradrenaline sympathisch
vasoconstrictief effect op de bloedvaten

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