Subcutaneous fatty tissue -
\Layer of loose connective tissue
Deeper tissues -
\Muscle, tendon, ligament, joint capsule, and bone
Basement Membrane Zone (BMZ) -
\Anchors the epidermis to the dermis, affected in blister formation. disrupted during
wound healing and must be reformed.
Lamina Lucida -
\Zone in the BMZ (electron-translucent zone)
Lamina Densa -
\Layer in the BMZ (electron-dense zone)
Major Proteins of BMZ -
\Fibronectin, Laminin, Type IV Collagen, Heparin Sulfate Proteoglycan
Stratum Basale -
\Layer of the epidermis - one cell thick. only layer of epidermis in which cells undergo
mitosis, forms the BMZ
Stratum Spinosum -
\Layer of the epidermis - Consists of several rows of more mature keratinocytes, which
appear spiny under a microscope.
Stratum Granulosum -
\Layer of the epidermis - Contains 3-5 flattened cell rows with increasing concentrations
of keratin.
Stratus Lucidum -
\Layer of the epidermis - Thin, clear layer of dead skin cells found in thick skin.
, Stratum Corneum -
\Layer of the epidermis - Consists of dead cells, sheds easily, contains keratin, functions
as a barrier to the environment and prevents trans-epidermal water loss.
Cells of the epidermis -
\Keratinocytes, Langerhans' cells, Melanocytes, Merkel's cells
Keratinocytes -
\Responsible for the toughness of the skin, produces keratin - the basic component of
hair, skin., and nails.
Langerhan's Cells -
\Help protect the body against infection - provide allergen recognition and assist with
immunity
Melanocytes -
\Responsible for producing melanin
Merkel's Cells -
\Mechanoreceptors that provide information on light tough sensation
Sebaceous Glands -
\Secrete sebum into hair follicles
Hair follicles -
\Contribute to appearance, body temperature, protection, and sensation
Eccrine sweat glands -
\Produce sweat to help regulate body temperature and assist with elimination of waste
products
Apocrine Sweat Glands -
\Produce sweat - responsible for body odor.
Nails -
\Made of dead cells containing keratin
Functions of the epidermis -
\Protective barrier to the outside environment, mitosis, pigmentation, self image, and
Vitamin D production.
Dermal Layers -
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