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NURS 4010 Psych Exam 1- medications

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NURS 4010 Psych Exam 1- medications Action of Benzodiazepines Increase the effect of GABA - Reduces neural excitability Action of SSRIs (selective serotonin reuptake inhibitors) Increase serotonin by inhibiting the reuptake of it Action of SNRIs (Selective serotonin-norepinephrine reup...

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  • May 8, 2024
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  • 2023/2024
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NURS 4010 Psych Exam 1- medications
Action of Benzodiazepines
Increase the effect of GABA - Reduces neural excitability


Action of SSRIs (selective serotonin reuptake inhibitors)
Increase serotonin by inhibiting the reuptake of it


Action of SNRIs (Selective serotonin-norepinephrine reuptake inhibitors)
Increase both serotonin and norepinephrine but inhibiting the reuptake


Action of TCA's (Tricyclic antidepressants)
Increases norepinephrine and serotonin
- some increase acetylcholine and histamine


Action of NDRI (norepinephrine-dopamine reuptake inhibitor)
Increase norepinephrine and dopamine by blocking reuptake


Action of MAOIs (monoamine oxidase inhibitors)
Increase monoamines
- interferes with enzyme that breaks down neurotransmitters


Action of Antipsychotics
Decrease dopamine
-atypical decrease dopamine and increase serotonin


What disorders can antidepressants treat other than depression?
Anxiety, OCD, panic disorder, eating disorders, sleep aid, pain syndromes


Classes of antidepressants
-Selective Serotonin Reuptake Inhibitors (SSRI)
-Serotonin-Norepinephrine Reuptake Inhibitors (SNRI)
Serotonin antagonist and reuptake inhibitor (SARI)
-Tricyclic Antidepressants (TCA)
-Monoamine Oxidase Inhibitors (MAOI)
-Psychotherapeutic Combinations
-Heterocyclics
-Atypical Antipsychotics


SSRI's
GOLD STANDARD for depression


Trintellix
SSRI
receptor agonist

, Celexa (citalopram)
SSRI


Lexapro (escitalopram)
SSRI


Prozac (fluoxetine)
SSRI
more exciting
longest half life


Luvox (fluvoamine)
SSRI


Paxil (paroxetine)
SSRI
sedative effects


Vilazodone (viibryd
SSRI and receptor agonist, lower sexual SE


Zoloft (sertraline)
SSRI


SSRI side effects
-often self limiting, go away with time
-agitation
-shakiness/jittery
-tremors
-headache
- sexual dysfunction
-Mild GI (nausea and diarrhea) because of high serotonin


Serotonin syndrome
POTENTIALLY TOXIC
-usually caused by combo of SSRI and MAOI or SSRI and ecstasy
-FIRST sign is HTN
-initial symptoms: mental status change (restlessness/agitation), lethargy, flushing, confusion,
tremors, diaphoresis, ataxia
-later signs: hyperthermia, renal failure, hypertonicity, seizure, death


Discontinuation syndrome (not lethal)
Occurs with abrupt stopping of medication
- can last 4-6 weeks and will go away with reinstitution of medications
-Flu like symptoms, insomnia, nausea, congestion, vertigo


SNRI's

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