MSN 571 Midterm|Complete Questions with 100% Correct Answers

MSN 571 Midterm|Complete Questions with 100% Correct Answers lithium check NA levels 2x per week until therapeutic levels and then monthly ED50 defined therapeutic response in 50% of the population pharmacogenetics the study of genetic factors that influence an individuals response to a specific drug pharmacogenomics the study of how genetics play a role in a persons response to drugs (MAT) Medication assisted therapy gold standard for treatment of opioid use disorder MAT drugs methadone, buprenorphine with or without naloxone, naltrexone Methadone full mu-opioid agonist. The binding at adequate doses can result in the reduction of heroin or other opioid use by decreased craving and withdrawal from other opioids methadone schedule II, 5 days to reach steady state, no ceiling effect. higher risk of overdose compared to buprenorphine patients who may need lower dose of methadone older than 60, use benzos, hx of cardiac arrhythmias, brady, QT prolongation, electrolyte abnormalitiies, asthma, copd methadone side effects dizziness, sedation, light headedness, N/V, contipation, diaphoresis, hypotension, cns depression, respiratory depression, methadone is recommended for pregnant patients with OUD Buprenorphine partial agonist at the mu receptor buprenorphine commonly combined with naloxone to reduce risk of medication misuse