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MSN 571 Midterm|Complete Questions with 100% Correct Answers

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MSN 571 Midterm|Complete Questions with 100% Correct Answers lithium check NA levels 2x per week until therapeutic levels and then monthly ED50 defined therapeutic response in 50% of the population pharmacogenetics the study of genetic factors that influence an individuals response to...

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  • May 23, 2024
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  • 2023/2024
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MSN 571 Midterm|Complete Questions with 100% Correct Answers
lithium
check NA levels 2x per week until therapeutic levels and then monthly


ED50
defined therapeutic response in 50% of the population


pharmacogenetics
the study of genetic factors that influence an individuals response to a specific drug


pharmacogenomics
the study of how genetics play a role in a persons response to drugs


(MAT) Medication assisted therapy
gold standard for treatment of opioid use disorder


MAT drugs
methadone, buprenorphine with or without naloxone, naltrexone


Methadone
full mu-opioid agonist. The binding at adequate doses can result in the reduction of heroin or other
opioid use by decreased craving and withdrawal from other opioids


methadone
schedule II, 5 days to reach steady state, no ceiling effect. higher risk of overdose compared to
buprenorphine


patients who may need lower dose of methadone
older than 60, use benzos, hx of cardiac arrhythmias, brady, QT prolongation, electrolyte
abnormalitiies, asthma, copd


methadone side effects
dizziness, sedation, light headedness, N/V, contipation, diaphoresis, hypotension, cns depression,
respiratory depression,


methadone
is recommended for pregnant patients with OUD


Buprenorphine
partial agonist at the mu receptor


buprenorphine
commonly combined with naloxone to reduce risk of medication misuse

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