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Unit 20 assignment 2
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RADIOPHARMACEUTICALS P3
Radiopharmaceuticals are a group of pharmaceutical drugs that have radioisotopes, which
can be used as diagnostic and therapeutic agents Radiopharmaceuticals emit radiation
themselves, which is different from contrast media; absorb or alter external
electromagnetism or ultrasounds Mostradiopharmaceutcals are combination of a radioactive
molecule, a radionuclide, that permits external detection and a biologically active molecule or
drug that acts as a carrier and determines
localization and bio distributions
Production of Radiopharmaceuticals
Radiopharmaceuticals contain small amounts of radioisotopes that can be produced by
irradiating a specific target inside a nuclear research reactor or particle accelerators, such as
cyclotrons In this assignment, I will be producton and detecton of radiopharmaceutcalss
RADIOPHARMACEUTICALS Radiopharmaceutcals are a group of pharmaceutcal drugs
that have radioisotopes, which can be used as diagnostc and therapeutc agentss
Radiopharmaceutcals emit radiaton themselves, which is diferent from contrast media;
absorb or alter extternal electromagnetsm or ultrasounds Most radiopharmaceutcals are
combinaton of a radioactve molecule, a radionuclide, that permits extternal detecton and a
biologically actve molecule or drug that acts as a carrier and determines localizaton and bio
distributons Productoon of Radiohaaraacࡸutcals Radiopharmaceutcals contain small amounts
of radioisotopes that can be produced by irradiatng a specifc target inside a nuclear research
reactor or partcle accelerators, such as cyclotronss hhe cyclotron is essentally a vacuum
chamber in which, by means of a magnetc feld parallel to itself – which is responsible for
defectng ions – and a system that generates an electric feld elementary partcles can be
accelerated to very high energiess hhese partcles will then interact with targets where
nuclear reactons take place that lead to obtaining radioactve isotopes and partcle beams
with the use in medicines Once produced, the radioisotopes are tagged on to certain
molecules based on biological characteristcs, which results in radiopharmaceutcalss
Ahhlicatoon of Radiohaaraacࡸutcals Radiopharmaceutcals can be used for either diagnostc
or therapeutc purposes depending on its specifc radiaton propertess hhe characteristc of
radioactve decay is what makes radioisotopes useful in their medical applicatons; however,
diferent applicatons will take advantage of radioactve emissions in diferent wayss In this
report, I will be discussing the diagnostc and therapeutc use of radiopharmaceutcalss
Diagonostc ahhlicatoons In diagnostc imaging, the radiopharmaceutcal is composed of a
radioisotope bond to an organic molecules hhe organic molecule conveys the radioisotope to
specifc organs, tssues or cellss hhe radioisotope is selected for its propertess Radioisotopes
emitting penetratng gamma rays are used for diagnostc imaging where the radiaton has to
escape the body before being detected by a specifc device (SPPECh/PEh cameras).s
hypically, the radiaton emited by isotope used for imaging vanishes completely afer day
through radioactve decay and normal body extcretons hhe most common isotopes for
imaging are hc-99m, I- 23, I- 3 , F- 8, etcs Tࡸcaonࡸtuam99a: hhe most widely used
radioisotope in medicine is technetum-99ms hechnetum99m is metastable nuclear isomer of
technetum-99 and has almost ideal characteristcs for a nuclear medicine scans hechnetum-
99m is used as a radioactve tracer and can be detected in the body by medical equipment
(Sgamma cameras).s It is well suited to the role, because it emits readily detectable gamma
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