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Chemotherapy and immunotherapy Questions and answers
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Chemotherapy and immunotherapy Questions and answers
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Chemotherapy and immunotherapyQuestions and answers
Cancer Treatment Goals: - ANSWER--cure
-control
-palliation
Cancer Treatment - ANSWER-Curative therapy
-surgery alone or periods of adjunctive systemic therapy
-timeframe to "cure" may differ according to the tumor and its characteristics
Control Treatment
-initial course and maintain therapy
Palliation goal - ANSWER--relief or control of symptoms
-maintain quality of life
-palliative care and treatment are not mutually exclusive and can take
concurrently
Personalized cancer medicine - ANSWER--genetic information is used to
customize decisions about: prevention, diagnosis, and treatment
Targeted Therapy - ANSWER--aims at a cancer's specific genes or proteins that
contribute to cancer growth and survival
-biopsy can help determine whether a timor has the specific target
Pharmacogenomics - ANSWER-study of genomic variation associated with drug
responses
The downside to personalized cancer medicine - ANSWER--not all types of
cancer have personalized treatment options
-costly
-time consuming
, -not covered by insurance
Antineoplastic therapy - ANSWER--use of chemicals given as a systemic therapy
for cancer
-mainstay for most solid tumors and hematologic cancers
-can off cure, control, or palliative care
chemotherapy cure - ANSWER--burkitts lymphoma
-wilms tumor
-neuroblastoma
-acute lymphocytic leukemia
-hodgkins lymphoma
-testicular cancer
Chemotherapy control - ANSWER--breast cancer
-non-hodgkins lymphoma
-small cell lung cancer
-ovarian cancer
Chemotherapy palliation - ANSWER--relieve pain
-relieve obstruction
-improve the sense of well being
Chemotherapy effect on cells - ANSWER--effective against dividing cells so
cancer cells escape death by staying in G0 phase (resting phase)
-Problem: presence of drug - resistant and non cycling cells
-as tumors get bigger, more cells become inactive and convert to G0
Chemotherapy classification of drugs - ANSWER-Classified by: molecular
structure
-mechanism of action
Two major categories
-cell cycle phase nonspecific
-cell cycle phase specific
-typically given in combination
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