NURS 3100 Final Exam|| 60 Questions|| Correct 100%

Bioavailability - ANSWER the physiologic ability of a drug to reach target cells and produce its effect. Half-life - ANSWER the time it takes for a drug to decrease in amount by half. Pharmacokinetics - ANSWER The study of medication movement throughout the body. The ability of a drug to cross plasma (cell) membranes in one of two ways (diffusion or active transport) Absorption - ANSWER site of administration-through cell membranes- to circulation. Factors that affect absorption include drug formulation/dissolution, dose, route of administration, size of the drug molecule, surface area of absorption site, GI motility, blood flow, pH, lipid solubility. Distribution - ANSWER transport of medications through the body after absorption or injection. Factors that affect distribution include a medication's affinity for certain areas of the body, medications also bind to plasma proteins creating a drug-protein complex. Drug-drug/drug-food interactions occur due to competition for receptor sites; the blood-brain and fetal-placental barriers prevent distribution