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Exam (elaborations)

Examenvragen farmacologie

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Examenvragen farmacologie 3de jaar verpleegkunde

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  • May 28, 2019
  • 7
  • 2017/2018
  • Exam (elaborations)
  • Unknown
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TAB 3.1: farmacologie


1. Bespreek Farmacodynamiek en farmacokinetiek

o Farmacokinetiek
 Wat gebeurt er in het lichaam met het geneesmiddel
 Wat het lichaam met het GM doet kan worden ingedeeld in 4 fasen:
1. Absorptie of resorptie
2. Distributie (Verdeling over de weefsels)
3. Metabolisatie
4. Excretie of eliminatie

o Farmacodynamiek
 Wat doet het geneesmiddel met het lichaam?
 Interactie van geneesmiddel met de receptor
- GM moet aan de receptor geraken om te werken
- GM is na veel membranen te passeren aangekomen op de plaats van de werking
(= Receptor)
- Door GM-receptor binding gebeurt er van alles in ons lichaam.

2. Bespreek: Vertraagde vrijstelling 2 pt

 Verlengde werking = slow release
 Voordelen
- Minder frequente inname nodig
Betere therapietrouw
Minder fluctuaties in plasmaspiegels
Minder nevenwerkingen




 Bevatten meestal equivalent van meerdere ‘normale’ dosissen geneesmiddel
Vb: Corvaton® 2 mg → Coruno® 16 mg
 Actieve stof wordt gedurende lange tijd (24u) gelijkmatig afgegeven
 Minder frequente inname nodig
* Betere therapietrouw
* Minder nevenwerkingen
 Mogen niet geplet worden (versterkt effect, toxiciteit, hoge piekspiegels)


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