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Samenvatting medische technieken
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(Behaalde score:19/20) Deze samenvatting bevat alle info uit de acco cursus gecombineerd met extra info en foto's uit de slides.
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Hoofdstuk: Medische technieken i.v.m bevruchting enimplantatie
1. In vitro-fertilisatie (ivf) = reageerbuisbevruchting =
proefbuisbevruchting
Eicellen worden net voor ovulatie geaspireerd uit ovarium
induceren van superovulatie
door toediening gonadotrope hormonen komen een aantal follikels tot rijping
Eicel wordt in vitro bevrucht met sperma van partner of donor
zygote laat men ontwikkelen tot vroege morulastadium en vervolgens wordt ze in uterus
moeder gebracht
meestal worden 5-tal bevruchte eicellen ingeplant omdat gemiddeld slecht 1/5 eicellen
zich implanteert
Eerste ‘proefbuisbaby’ = Louise Brown
Variant van ivf methode:
1) Eicel en sperma in ampulla eileider brengen en dan verdere natuurlijke ontwikkeling zijn
gang laten gaan
2) Zygote die in vitro ontstaan is onmiddellijk in eileider plaatsen
Beiden niet steeds toepasbaar door deficiënt transport van eicel in eileider of
ondoorgankelijkheid van eileider
2. Intracytoplasmatische sperma-injectie of ICSI
1 zaadcel wordt rechtstreeks in 1 eicel geïnjecteerd
De bevruchting gebeurt dus kunstmatig
Eicellen worden na pick-up uit eierstokken onder microscoop bekeken en ontdaan van
cumuluscellen deels manueel met micropipet, deels enzymatisch
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