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MCB 2010 CHAPTER 18
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Exam of 5 pages for the course NUR 240 EXAM 2 Practice Questions. at NUR 240 EXAM 2 Practice Questions. (MCB 2010 CHAPTER 18)
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MCB 2010 CHAPTER 18A patient's serum is tested using the complement fixation test. If hemolysis occurs -
ANS-complement was not fixed by antibodies in the patient's serum and was available
to the antibodies, thus inducing lysis of sheep red blood cells
A vaccine comprised of the nonpathogenic antigens is called a - ANS-subunit vaccine.
Acellylar vaccines - ANS-fractions of disrupted bacteria cell wall pertusis
Adjuvant - ANS-a substance added to a vaccine to increase its effectiveness.
anti HISG - ANS-An antibody that reacts specifically with human antibodies
Attenuated Vaccines - ANS-Lifelong immunity, MMR, can back mutate to virulent form.
Attenuated whole agent vaccine - ANS-A vaccine containing live, attenuated
(weakened) microorganisms.
Complement Fixation - ANS-the process in which complement combines with an
antigen antibody complex.
conjugated vaccines - ANS-are useful because infants respond poorly to
polysaccharides
Conjugated vaccines - ANS-Polysaccharides + protein. H influenzae + Diphteria toxoid
Direct agglutination - ANS-what is it called when IgM antibodies cross-link with particles
Direct agglutination test - ANS-the use of known antibodies to identify an unknown cell
bound antigen.
Direct FA test - ANS-a fluorescent anitbody test to detect ANTIGENS
ELISA - ANS-Enzyme linked immunosorbetn assay. A group of serological tests that
use enzyme reactions as indicators.
FACS - ANS-Fluorescence activated cell sorter. A modification of a flow cytometer that
counts and sorts cells labeled with fluorescent antibodies.
, FACS - ANS-used to count CD4+ and follow progression of AIDS. Quick, sensitive and
very specific
For both the direct and the indirect ELISA - ANS-substrate is added as a final step
Hemagglutination - ANS-the clumping of red blood cells.
Hemagglutination in an immunoassay - ANS-involves antibodies cross-linking
erythrocytes
Herd Immunity - ANS-The phenomenon whereby those people in a population who
have no protective immunity against a pathogen are largely protected from infection
when the majority of the population is resistant to the pathogen.
Humanized antibody - ANS-Monoclonal antibodies that are partly or fully human
proteins
Hybridoma - ANS-the fusion of cultured myeloma cells with antibody producing spleen
cells.
Immunodiffusion test - ANS-a test consisting of precipitation reactions carried out in an
agar gel medium
Immunoelectrophoresis - ANS-The identification of proteins by electrophoretic
separation followed by serological testing
In a complement-fixation test, for a serum sample containing antibody against the target
antigen - ANS-complement will be fixed, and sheep red blood cells will not lyse
Inactivated whole agent killed - ANS-influenza, rabies, polio, pneumococcal pneumonia,
cholera, pertusis and typhoid.
Indirect (passive) agglutination test - ANS-An agglutination test using soluble antigens
attached to latex or other small particles.
Indirect agglutination - ANS-what is it called when an anti-immunoglobulin is used in an
agglutination reaction
Indirect FA test - ANS-a fluorexcent antibody test to detect ANTIBODY
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