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Immunology Kuby Chapter 13
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Immunology Kuby Chapter 13
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Immunology Kuby Chapter 13- ANS-a
- ANS-b
- ANS-e
_______ describes the action of antibodies whereby antibodies bind to a pathogen and
prevent the pathogen from interacting with cell receptors.
Antibody-dependent cell-mediated cytotoxicity
Antigen presentation
Complement fixation
Neutralization
Opsonization - ANS-Neutralization
1. What is the effector cells/molecules of humoral and cell-mediated branch of
immunity? - ANS-
2. Describe neutralization, opsonization, complement fixation, and ADCC. -
ANS-Neutralization- inhibiting pathogen from entering host
Opsonization- antigen is coated by antibody to be more easily detected
Specific FcR for different antibodies...
FcαR binds IgA
FcγR binds IgG
FcεR binds IgE
complement fixation- classical complement activation, IgM and IgG, C3b coats antigen
and is deted by C3b receptors to form MAC
ADCC- antibody bound to tumorous cells then NK binds and releases cytotoxic
chemicals (Perforin and granzyme)-induced apoptosis
3. Antibodies play a major role is the above, but what else 'helps' the each process? -
ANS-
4. What antibody classes can be produced by plasma cells? - ANS-IgG, IgA, IgE
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