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IBHRE CEPS 2018 EXAM – QUESTIONS AND ANSWERS

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IBHRE CEPS 2018 EXAM – QUESTIONS AND ANSWERS

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  • June 3, 2024
  • 5
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
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IBHRE CEPS 2018 EXAM – QUESTIONS
AND ANSWERS
Class 1 Anti-Arrhythmic Mechanism - -Sodium (Na) Channel Blockers

-Class II Anti-Arrhythmic Mechanism - -Beta Blockers

-Class III Anti-Arrhythmic Mechanism - -Potassium (K) Channel Blockers

-Class IV Anti-Arrhythmic Mechanism - -L-Type Calcium (Ca) Channel
Blocker

-Class Ia drugs - --Quinidine (rarely used)
-Procainamide
-Disopyramide.

Na Channel blockers that raise APD

-Class Ib drugs - --Lidocaine
-Mexiletine
-Phenytoin

Na Channel blockers that slightly lower APD

-Class Ic drugs - --Propafenone
-Flecainide

Na Channel blockers that don't change APD

-Class II Drugs - --Propranolol
-Atenolol
-Esmolol
-Metoprolol

Beta-Blockers. (β-blockers)

-Class III Drugs - --Amiodarone
-Dronedarone
-Sotalol
-Ibutilide
-Bretylium

Prolong APD (K Channel Blocker)

, -Class IV Drugs - --Verapamil
-Diltiazem

L-Type Ca Channel Blockers

-Phase 0 AP - --Depolarization
-Rapid Na+ Channels are stimulated to open, flooding the cell with positive
sodium ions.
-Depolarizatoin of one cell triggers the Na+ channels in surrounding cells to
open causing wave of propogation.

-Phase 1 AP - --Initial Stage of Repolarization
-Inactivation of the fast Na+ Channels

-Phase 2 AP - --Plateau Phase
-Sustained by a balance between inward movement of Ca2+ through L-type
calcium channels (opened in response to depolarization) and outward
movement of K+ through the slow K+ channel.
-Reduced potassium ion permeability

-Phase 3 AP - --Rapid Repolarization Phase
-Ca2+ channels close
-Slow K+ remains open
-Ionic pumps restore ion concentrations back to balanced states of pre-AP

-Phase 4 AP - --Resting Membrane Potential

-Alpha Adrenergic Receptor site effect - -Vasoconstriction

-Beta-1 Adrenergic Receptor site effect - -Cardiac Stimulation

We have 1 heart, 2 lungs.

-Beta-2 Adrenergic Receptor site effect - -Lung Broncho-dilation

We have 1 heart, 2 lungs.

-Cholinergic receptor effect - -Cardiac Depression

-Sympathetic Nervous System - -

-Unit for Frequency - -Hertz Hz - Cycles / S

-Unit for Force (Exertion) - -Newton N - Kg * M/s^2

-Unit for Energy - -Joule J - Kg * M^2/S^2

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