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Samenvatting morfologie van het spijsverteringsstelsel

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Course
Morfologie van het spijsverteringsstelsel (E0I51A)

Institution
Katholieke Universiteit Leuven (KU Leuven)

Dit is een samenvatting van de slides in combinatie met de cursustekst voor het deel morfologie van het vak MFP vh spijsverteringsstelsel van het nieuwe curriculum geneeskunde dat in 2e semester in 1e bac gegeven wordt

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Uploaded on June 5, 2024
Number of pages 74
Written in 2023/2024
Type Summary

morfologie
spijsverteringsstelsel
spijsvertering
mfp

Institution
Katholieke Universiteit Leuven (KU Leuven)
Education
Geneeskunde
Course
Morfologie van het spijsverteringsstelsel (E0I51A)

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MORFOLOGIE VH
SPIJSVERTERINGSSTELSEL
INHOUD
Introductieles .............................................................................................................................. 4
Functie ................................................................................................................................................ 4
opbouw (macro- & microscopie) ........................................................................................................ 4
bevloeiing ............................................................................................................................................ 6
arteries ............................................................................................................................................ 6
venen & lymfevaten ........................................................................................................................ 6
bezenuwing ......................................................................................................................................... 7
opbouw : anatomisch ...................................................................................................................... 7
opbouw : functioneel ...................................................................................................................... 8
opbouw : histologie ......................................................................................................................... 8
craniale zenuwen ............................................................................................................................ 8
autonome zenuwstelsel ................................................................................................................ 10
ziekte v hirschprung ...................................................................................................................... 12
immuniteit ........................................................................................................................................ 13
GALT = gut associated lympho-epithelial tissue............................................................................ 13
mondholte & keelengte ............................................................................................................. 17
vestibulum oris.................................................................................................................................. 17
cavum oris proprium ......................................................................................................................... 20
mondvloer ..................................................................................................................................... 20
lingua ............................................................................................................................................ 22
palatum durum & molle ................................................................................................................ 26
Speekselklieren.......................................................................................................................... 29
inleiding............................................................................................................................................. 29
histologie........................................................................................................................................... 30
lozingsgangen ............................................................................................................................... 30
acini ............................................................................................................................................... 30
macroscopie ...................................................................................................................................... 31
glandula parotis ............................................................................................................................ 31
glandula submandibularis ............................................................................................................. 32

1

, glandula sublingualis .................................................................................................................... 33
bezenuwing ....................................................................................................................................... 33
pharynx ..................................................................................................................................... 33
Nasopharynx (= anterieure wand) .................................................................................................... 34
laterale & posterieure wand ............................................................................................................. 34
tunica mucosa ............................................................................................................................... 34
tunica muscularis pharyngis ......................................................................................................... 35
slokdarm ................................................................................................................................... 37
macroscopie ...................................................................................................................................... 37
algemene opbouw......................................................................................................................... 37
bloedvoorziening ........................................................................................................................... 38
bezenuwing ................................................................................................................................... 38
microscopie ....................................................................................................................................... 39
mucosa .......................................................................................................................................... 39
submucosa .................................................................................................................................... 40
muscularis propria ........................................................................................................................ 40
adventitia/serosa .......................................................................................................................... 41
pathologie ......................................................................................................................................... 41
de maag..................................................................................................................................... 41
functie ............................................................................................................................................... 41
macroscopie ...................................................................................................................................... 41
bloedvoorziening ........................................................................................................................... 43
bezenuwing ................................................................................................................................... 43
microscopie ....................................................................................................................................... 43
mucosa .......................................................................................................................................... 43
muscularis propria ........................................................................................................................ 47
pathologie ......................................................................................................................................... 47
dunne darm ............................................................................................................................... 48
macroscopie ...................................................................................................................................... 48
bevloeiing ...................................................................................................................................... 49
bezenuwing ................................................................................................................................... 50
microscopie ....................................................................................................................................... 50
mucosa .......................................................................................................................................... 52
submucosa, muscularis, serosa ..................................................................................................... 53

2

, pathologie ......................................................................................................................................... 53
dikke darm ................................................................................................................................ 54
macroscopie ...................................................................................................................................... 54
caecum .......................................................................................................................................... 54
apendix vermiformis ..................................................................................................................... 54
colon .............................................................................................................................................. 55
rectum ........................................................................................................................................... 57
bloedvoorziening ........................................................................................................................... 57
bezenuwing ................................................................................................................................... 58
microscopie ....................................................................................................................................... 59
mucosa .......................................................................................................................................... 59
submucosa .................................................................................................................................... 59
muscularis propria ........................................................................................................................ 60
serosa/adventitia .......................................................................................................................... 60
pathologie ......................................................................................................................................... 60
de lever ..................................................................................................................................... 60
macroscopie ...................................................................................................................................... 61
bloedvoorziening ........................................................................................................................... 65
microscopie ....................................................................................................................................... 65
membraandomeinen vd hepatocyt ............................................................................................... 67
pathologie : levercirrose ................................................................................................................... 67
galwegen ................................................................................................................................... 68
galwegen ........................................................................................................................................... 68
microscopie ....................................................................................................................................... 70
pathologie ......................................................................................................................................... 70
pancreas .................................................................................................................................... 71
macroscopie ...................................................................................................................................... 71
bevloeing........................................................................................................................................... 72
microscopie ....................................................................................................................................... 73
exocriene pancreas ....................................................................................................................... 73
endocriene pancreas ..................................................................................................................... 73
pathologie ......................................................................................................................................... 74

3

, INTRODUCTIELES
FUNCTIE
Propulsie : voortstuwen v voedsel v mond naar anus (peristaltiek)
Vertering v voeding
- Zure pH → maag
- Enzymes → speekselklieren, maag, pancreas
Absorptie (water & voedingstoffen) → dundarm
Detoxificatie (opgenomen voedingsstoffen) → lever
Secretie (interne & externe giftige substanties) → colon, lever
Afweer (immuunsysteem) → GALT : want alles wat in maag = buitenwereld → moeten ons kunnen
verdedigen

OPBOUW (MACRO- & MICROSCOPIE)

4 lagen:
Mucosa
- Epitheel (+ basale membraan)
- Lamina propria (losmazig bindweefsel, capillairen, GALT, zenuwvezels)
- Muscularis mucosae
Submucosa
- Losmazig bindweefsel
- Submucosale klieren

4

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