Exam (elaborations)

NABP NAPLEX Exam_NAPLEX Dumps Released V8.02_DumpsBase

0 purchase

Course
NABP NAPLEX

Institution
NABP NAPLEX

[Show more]

Preview 4 out of 50 pages

View example

Uploaded on June 6, 2024
Number of pages 50
Written in 2023/2024
Type Exam (elaborations)
Contains Questions & answers

nabp naplex examnaplex dumps released v802dumps
1which of the following represents the major rou

Institution NABP NAPLEX
Course NABP NAPLEX

smartgrades Member since 3 year 2538 documents sold

308

100

$11.99

Add to cart

Add to wishlist

100% satisfaction guarantee
Immediately available after payment
Both online and in PDF
No strings attached

NABP NAPLEX Exam_NAPLEX Dumps Released V8.02_DumpsBase
1.Which of the following represents the major route of metabolism for acetaminophen?
A.Glucuronidation
B.Sulfation
C.Cytochrome P-450 oxidation
D.Direct renal excretion
E.Plasma breakdown Answer: A Explanation:
Acetaminophen is metabolized by choices A through D. The major route is glucuronidation catalyzed by UDP-glucuronyl transferase in the liver. Sulfation is the next most common route and is the target mechanism for NAC therapy. Oxidation by cytochrome P-450 results in the formation of N-
acetyl-pbenzoquinone imine, which is responsible for the hepatic necrosis caused by acetaminophen overdose. Direct renal excretion represents approximately 5% of the metabolism of acetaminophen. Plasma metabolism
of acetaminophen does not generally occur.
2.A 15-year-old presents with 6 days of nasal congestion with thin, clear rhinorrhea. She notes mild facial pain but has had no fevers. She feels her symptoms are improving.
What is the most likely cause of her symptoms?
A.Streptococcus pneumoniae
B.Viral
C.Moraxella catarrhalis
D.Haemophilus influenzae
E.Staphylococcus aureus Answer: B
Explanation:
This patient shows symptoms of acute sinusitis. The most common etiology of which is viruses. Indications that an infection is viral as opposed to bacterial included a shorter infection tie (less than 10 days) and no purulent discharge (hers is watery).
She does not show any evidence of a complication developing and even notes that her symptoms are improving. If her symptoms were attributed to a bacterium, then the most common cause of acute sinusitis is Streptococcus pneumoniae followed by Haemophilus influenza, then Moraxella catarrhalis. Anaerobic species such as Bacteroides fragilis and Staphylococcus aureus are more commonly found in patients with chronic sinusitis (sinusitis lasting longer than 12 weeks). This is important to realize before indiscriminately providing antibiotics for these patients.
3.A 72-year-old woman suffers from a major depressive episode. She NABP NAPLEX Exam_NAPLEX Dumps Released V8.02_DumpsBase
has a history of coronary artery disease, atrial fibrillation on anticoagulation therapy, sick sinus NABP NAPLEX Exam_NAPLEX Dumps Released V8.02_DumpsBase
syndrome, glaucoma, and chronic obstructive pulmonary disease.
Which of the following medications is most appropriate for the treatment of her depression?
A.Amitriptyline
B.Nortriptyline
C.Doxepin
D.Fluvoxamine
E.Escitalopra
m Answer: E Explanation:
In older adults, selection of antidepressant medication should be done with various considerations in mind, most notably side effects and risk of drug-drug interactions. The tricyclic antidepressants (TCAs), as discussed on question 50, have various side effects including cardiac conduction abnormalities and drug-drug interactions that make them undesirable for the treatment of depression in older adults. A selective serotonin reuptake
inhibitor is more favorable than a TCA in this patient. Fluvoxamine has a high risk for drug-drug interactions, whereas escitalopram does not.
Fluvoxamine also has high protein binding, and can therefore interact with anticoagulant medications, such a warfarin. Therefore, of the medications listed, escitalopram is the most appropriate in this patient. In older adults, psychotropic medications should be started at a low dose and titrated up slowly to the lowest effective dose.
4.A 20-year-old student came to the emergency department with primary complaints of palpitations, low-grade fever, and anxiety for 2 months. She reports that she is irritable and suffers severe mood swings that is interfering with her sleep and relationships (she admits to crying spells and frequent fights with friends and family). She has also lost 12 pounds in the past 2 months with no apparent alteration in her diet or physical activity (though she is happy with her weight loss). She denies any past medical problems, though her friends have always been worried that she eats too little.
Her temperature is 38.0 C (100.4 F), blood pressure is 148/62 mm Hg, pulse is 122/min and regular, and respiratory rate is 28/min. Examination reveals a bruit heard over the anterior neck, fine tremor of the hands, and warm, moist skin. Her eyes and eyelids do not move together during finger
following test (with steady head).
Laboratory work is sent, including a thyroid panel, but will not be available until tomorrow morning.
Which of the following is the most appropriate initial management at this time?
A.Diltiazem therapy
B.Iodine therapy
C.Methimazole therapy NABP NAPLEX Exam_NAPLEX Dumps Released V8.02_DumpsBase
D.Propranolol therapy

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller smartgrades. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $11.99. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

69052 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 15 years now

Start selling

Exam (elaborations)

NABP NAPLEX Exam_NAPLEX Dumps Released V8.02_DumpsBase

Document information

Subjects

Written for

Seller

Reviews received

Content preview