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Biochemie Samenvatting 2.4 informatorium Vetten
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Goede samenvatting van Biochemie van het informatorium over vetten
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BiochemieSamenvatting
Informatorium Voeding en Diëtetiek
Hoofdstuk 4. Vertering, opname en
stofwisseling van vetten
4.1 Vertering van vetten en opname uit de darm
Triglyceriden splitsen in glycerol, vetzuren en monoglyceride voordat ze door darmwand (mucosa)
opgenomen kunnen worden, dit met behulp van pancreaslipase (hydroliseren). Gal (door galblaas)
speelt een belangrijke rol zorgen ervoor dat vet uit voeding mengt met de waterige inhoud van de
darm vorming micellen (emulsie). Resorptie vetten 98%, wat bijna niet in feces zit, wanneer wel
stoornis vetvertering of resorptie (steatorroe).
Darmwandcellen nemen de producten of en maken hier voor een groot deel weer triglyceriden van
met behulp van enzym thiokinase. Verzadigde vetten met korte middellange ketens (C4:0-C10-0)
worden niet in triglyceriden ingebouwd, maar meteen in bloed opgenomen en via poortader naar de
lever getransporteerd voor verdere stofwisseling. De gemaakte veresterde triglyceriden worden door
darmwandcellen ingepakt in chylomicronen die in lymfe uitgescheiden (ductus thoracicus) en komen
via de bovenste holle ader (vena subclavia) in de bloedbaan terecht.
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