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Samenvatting Q5 CSI smv
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Samenvatting CSI Q5 met ethiek, morele dilemma's, prenatale screening en diagnostie, dure medicijnen en targeted therapy, en diagnostiek en screening bij kanker
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LiekeSchonberger
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CSI Q5Samenvatting
Lieke Schönberger
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Morele dilemma’s ................................................................................................................................... 5
Ethische problemen............................................................................................................................. 5
Moraal en moraliteit ........................................................................................................................... 5
Ethische uitspraken ............................................................................................................................. 6
Methodische aanpak ........................................................................................................................... 6
Gebruik van morele termen ................................................................................................................ 7
Recht en ethiek.................................................................................................................................... 8
Morele theorieën ................................................................................................................................ 9
Meta-ethiek ......................................................................................................................................... 9
Redeneren, argumenteren en ethische principes ............................................................................... 9
Wat is een argument? ................................................................................................................... 10
Ethisch argumenteren ................................................................................................................... 10
Autonomie ......................................................................................................................................... 10
Paternalisme .................................................................................................................................. 10
Verantwoord medisch handelen ....................................................................................................... 11
Prenatale screening en diagnostiek ...................................................................................................... 13
Prenatale screening ........................................................................................................................... 13
Screening op T21, T18 en T13 ........................................................................................................... 14
Testkarakteristieken .......................................................................................................................... 15
Combinatietest .................................................................................................................................. 15
NIPT ................................................................................................................................................... 16
Invasief prenatale testen ................................................................................................................... 16
SEO (20 weken echo) ......................................................................................................................... 17
GUO (Geavanceerd Ultrageluid Onderzoek) ..................................................................................... 18
Zwangerschapsbeëindiging ............................................................................................................... 18
Dure medicijnen en targeted therapy ................................................................................................... 20
Ipilimumab..................................................................................................................................... 20
Nederlandse Vereniging voor Medische Oncologie (NVMO) ........................................................ 20
Patent ............................................................................................................................................ 20
Monoclonale antilichamen ............................................................................................................ 21
Kostenbeperking............................................................................................................................ 21
Medicijnsluis .................................................................................................................................. 21
Genetica borstkanker en eierstokkanker .......................................................................................... 22
Moleculaire doelgerichte behandelingen ......................................................................................... 22
Hiërarchie in de doelwitten ........................................................................................................... 23
, Tumorboard....................................................................................................................................... 24
Drug development............................................................................................................................. 24
Kanker; diagnose en screening .............................................................................................................. 26
Principes van vroege diagnostiek ...................................................................................................... 26
Screening voor kanker ....................................................................................................................... 27
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