NR566 Final (Advanced Pharmacology for Care of the Family) Questions and Answers

NR566 Final (Advanced Pharmacology for Care of the Family) Anti-Androgens - Answer- Finasteride (Propecia) Leuprolide (Eligard, Lupron, Lupron Depot) Spironolactone (Aldactone) Finasteride (Propecia, Proscar) - Answer- blocks conversion of testosterone to dihydrotesterone Used to tx: -BPH -male pattern baldness 3 months of therapy need to see benefits Stopping, reverses effect w/in 12 months Adverse side effects: - Decreased libido -Impotence dutasteride (Avodart) - Answer- 5-alpha reductase inhibitor used to tx: BPH Can stay in serum up to 6 mon after discontinuing can be absorbed through skin pregnant woman shouldn't handle capsules (fetal anomaly in male fetus) Adverse Effects decreased libido Impotence Leuprolide Acetate (Lupron) - Answer- Luteinizing hormone - releasing agonist create reversible: -orchiectomy state -oophorectomy state Used to tx: - advanced prostatic cancer - Management of endometriosis - Uterine fibroids - polycystic ovarian disease - central precocious puberty in peds Flutamide (Eulexin, Euflex) - Answer- Truly non-steroidal agent Used to tx: