MARYVILLE NURS 660 EXAM
Which medication is contraindicated with liver impairment? - correct answer Atomoxine (Straterra)
What is one of the birth defects associated with Litihum? - correct answer Ebstein's anomaly
Which SSRI drug causes cardiovascular malformations in the first trim...
Which medication is contraindicated with liver impairment? - correct answer✔✔ Atomoxine (Straterra)
What is one of the birth defects associated with Litihum? - correct answer✔✔ Ebstein's anomaly
Which SSRI drug causes cardiovascular malformations in the first trimester of pregnancy? - correct
answer✔✔ Paroxetine (Paxil)
Mechanism of action of a stimulant for ADHD Methylphenidate and amphetamine? - correct answer✔✔
increases the intrasynaptic levels of both dopamine and norepinephrine
What causes nicotine withdrawal symptoms? - correct answer✔✔ Nicotine alpha 4 beta 2 post synaptic
receptors desensitizes receptors which leads to addiction. Re-sensitization of the nicotine receptors
leads to withdrawal
A patient diagnosed with ADHD can't stay focused or solve work-related problems difficulty maintaining
attention sustained and problem-solving. What area of the brain is involved? - correct answer✔✔ Dorsal
lateral prefontal cortex (CTSC loop)
What part of the brain is associated with selective attention? - correct answer✔✔ Dorsal anterior
singlunate
What part of the brain is associated with hyperactivity? - correct answer✔✔ Prefrontal motor cortex
What part of the brain is associated with impulsivity? - correct answer✔✔ Orbitofrontal cortex
, Atomoxetine (Strattera) lacks abuse potential because of what - correct answer✔✔ increases dopamine
in the dorsal prefrontal cortex and not in the nucleus accumbens
What fetal malformation does valproate cause? - correct answer✔✔ Spina bifida
What region of the brain is hypothesized to cause impulsivity? - correct answer✔✔ ventral striatum
What region of the brain controls compulsivity? - correct answer✔✔ Dorsal striatum
What is the MOA of atomoxetine (Strattera)? - correct answer✔✔ Selective Norepinephrine Reuptake
Inhibitor: Boosts neurotransmitter norepinephrine/ noradrenaline and may also increase dopamine in
profrontal cortex • Blocks norepinephrine reuptake pumps, also known as norepinephrine transporters
•
Amaloid precursor protein is first cleaved by what enzyme - correct answer✔✔ Alpha-secretase
What does paroxetine do to Straterra in the body? - correct answer✔✔ increases the effect of the drug
in the body
If a patient is taking paroxetine and starts Straterra what should change about the Straterra dose? -
correct answer✔✔ The dose should be decreased
An Alzheimer's patient has been taking 4mg of rivastigmine what side effects might you anticipate and
why? - correct answer✔✔ GI side effects; inhibits peripheral uptake of ACH and butyrycholine
Which neurotransmitters lead to eurphoria and abuse in a patient with marijuana abuse and ADHD. -
correct answer✔✔ Pulsatile delivery of stimulants can cause a frequent and rapid delivery amplifying
phasic firing of NE and DA. Phasic firing is associated with reward, euphoria, and abuse
What does alcohol do to the CYP 450 system? - correct answer✔✔ lowers the rate of drug metabolism
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller DOCUFLASH. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $10.49. You're not tied to anything after your purchase.
