Lecture notes BI505 Infection And Immunity (BIOS5050) on Viruses and the Immune Response to Viral Infection
7 views 0 purchase
Course
BI505 Infection And Immunity (BIOS5050)
Institution
The University Of Kent (UKC)
Unlock your academic potential with my notes on Immunity and Infection, tailored specifically for students pursuing Biomedical Science, Biochemistry, Immunology, Biology, Biomedical Engineering, Pharmacology, Medicine and Nursing. These notes are perfect for anyone looking to excel in their studies...
Dr elizbeth curling, dr gary robinson, alex moores
All classes
Subjects
viruses
viral infection
immunity and infection
university of kent
bios5050
bioscience
immune response
diease
immun
viruses and the immune response to viral infection
immune response to viral infection
Written for
The University of Kent (UKC)
Unknown
BI505 Infection And Immunity (BIOS5050)
All documents for this subject (22)
Seller
Follow
morgan_helene
Content preview
Lecture: Infection and Immunity
Date: Friday 2nd February
Time: 1 – 2pm
Viruses and the Immune Response to Viral Infection
We are going to discuss how viruses enter the immune system and its response to them.
Learning objectives:
1) Classification of DNA and RNA virus families
2) The influenza virus and its structures effect on getting in and out of the cell.
3) Virus infection via receptors and replication within cells (i.e. polio)
4) Time scale of different responses (innate and adaptive)
5) The role of interferons, natural killer cells and their fight against viral infections
6) The role of the cytotoxic T cells – these are good at recognising an infected cell and
causes it to go into apoptosis.
7) The immune synapse/cell cytotoxicity methods
8) Measurements of cytotoxicity in the lab.
9) The concept of self MHC restriction
Viral classification diagram – size and shapes of viruses.
Classification criteria, split up into RNA and DNA. The shape can either be helical or
icosahedral. Some present as tiny, whereas DNA viruses are large reaching up to 130 -280kb.
Schematic diagram of influenza virus
The outside of this virus has a lipid bilayer; therefore, it is an enveloped virus as it has taken
some of the lipid bilayer from the infected cell.
1) Hemagglutinin – there to bind to sialic acid (a type of sugar). (16 subtypes)
2) Neuraminidase – an enzyme that cuts the plasma membrane and allows the virus to
leave the cell. (9 subtypes)
1
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller morgan_helene. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.96. You're not tied to anything after your purchase.
