100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Lecture notes BIOS5030 Cell Biology (BIOS5030) on Tubulin and microtubules $13.96   Add to cart

Class notes

Lecture notes BIOS5030 Cell Biology (BIOS5030) on Tubulin and microtubules

 7 views  0 purchase
  • Course
  • Institution

Unlock your academic potential with my notes on Cell Biology, tailored specifically for students pursuing Biomedical Science, Biochemistry, Immunology, Biology, Biomedical Engineering, Pharmacology, Medicine and Nursing. These notes are perfect for anyone looking to excel in their studies and gain ...

[Show more]

Preview 1 out of 4  pages

  • June 13, 2024
  • 4
  • 2023/2024
  • Class notes
  • Dr gourlay, mulvihill, shepherd, mulligan, goult
  • All classes
  • Unknown
avatar-seller
Week Number: 13
Seminar Date: Wednesday 1st November
Time: 10am-11am
Module: Cell Biology BI503



Tubulin and microtubules

Today we are going to cover microtubules and how they’re made.

Image of a mitotic cell
This shows long fibers (microtubules) leading into the central part and thicker bundles of
microtubules forming the spindle ball bundles. The spindle ball body is where the
microtubules are born, the asp microtubules help position the spindle ball body.

Microtubular assemblies

Microtubule dynamics highlighted by GFP-EB1, bind to the GTP cap of growing
microtubules. All the white blobs race around inside the cytoplasm, these white blobs mark
the ends of microtubules. Microtubule networks in the cytoplasm are highly dynamic and are
constantly being made and used.

Microtubule and endoplasmic reticulum dynamics at the edge of the cell, note the dynamic
interplay between these systems. The red lines represent microtubules spreading to the
leading edge of the cell and then shrinking rapidly away. This is a fundamental property
of microtubules.

The green lines represent the endoplasmic reticulum. Most organelles within the cells are
being transported along the microtubules, this is why the red and green lines interconnect.
These are train track structures transporting material throughout the cell.

Microtubule dependent transport/movement in cells

One of the main roles of microtubules is to transport membrane vesicles and organelles
through the cytoplasm. For example, Messenger RNA. Microtubules interface with actin
filaments to form a mesh work at the edge of the cell. The motor proteins bind to the
microtubules, using the microtubular motor proteins and the actin filaments.

The transport process will be covered in the next lecture.
Fundamental principles of microtubules.

Every microtubule filament is made of two proteins (heterodimer):

1. Alpha tubulin - this subunit is exposed on the - end of the microtubule.
2. Beta tubulin – this subunit is exposed on the + end of the microtubule.




1

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller morgan_helene. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $13.96. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

79271 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$13.96
  • (0)
  Add to cart