Lecture notes BIOS5030 Cell Biology (BIOS5030) on Intercellular transport
8 views 0 purchase
Course
BIOS5030 Cell Biology (BIOS5030)
Institution
The University Of Kent (UKC)
Unlock your academic potential with my notes on Cell Biology, tailored specifically for students pursuing Biomedical Science, Biochemistry, Biology, Biomedical Engineering, Pharmacology, Medicine and Nursing. These notes are perfect for anyone looking to excel in their studies and gain a deep under...
Monoclonal antibodies- research topic. Used to treat autoimmune disease, cancer.
Economically wealthy countries have access to these, but others don’t. The reason they are
expensive is because we must make them using cells. Goal is to make them cheaper, to do
that we need to understand the secretory pathway.
If you are interested in nuclear transport or other pathways, then you can explore this in your
textbook.
All slides have alt text – this will cover the lecture information.
Eukaryotic cells have membrane enclosed in organelles.
In a bacterium cell, proteins move through the cytoplasm, whereas in larger cells it is
impossible for this to happen.
à Membranes
o Barrier to separate contents of organelles from the rest of cytoplasm
o Selectively permeable
o Increase surface area for biochemical reactions.
à Organelles
o Each contain a unique set of proteins.
o Concentrate subsets of molecules
Not all cells are the same. In some cells we turn on some sets of genes (i.e. histone,
chromatin etc), other cells express more types of genes i.e. a plasma cell has more
endoplasmic reticulum.
Following the secretory pathway – this will be picked up with Dr Gourlay later.
o ER – Endoplasmic reticulum.
o 50 % of cellular membrane is in the ER.
o Rough ER (has ribosomes attached to it) Vs smooth ER (does not have ribosomes)
Why do we cover ER in Ribosomes? We need lots of proteins in the ER, this is done using
membrane bound ribosomes. The translation starts in the cytosol, which has a signal
sequence in the growing polypeptide chain that tells the ribosome that the protein needs to
be transferred to the ER. At this point it will be signaled to dock and feed the protein into the
1
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller morgan_helene. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.71. You're not tied to anything after your purchase.
