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GMS 6531 Homework.
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Exam of 9 pages for the course 6521 Advanced Pharmacology Final at 6521 Advanced Pharmacology Final (GMS 6531 Homework.)
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GMS 6531 HomeworkThe majority of hormones secreted by the hypothalamus affect what structure? -
ANS-Anterior pituitary
The pineal gland secretes what hormone? - ANS-melatonin
Vitamin D synthesis is completed in what structure? - ANS-Kidneys
Osteocalcin is which type of hormone? - ANS-Peptide
Which drug would be used to help maintain body mass during treatment for HIV? -
ANS-Somatropin
Octreotide mimics a hormone released from which structure? - ANS-Hypothalamus
Which drug blocks the effects of GH excess without altering GH expression? -
ANS-Pegvisomant
Which drug would be used to treat unwanted lactation that is not associated with
pregnancy or childbirth? - ANS-Bromocriptine
On-and-off dosing of GnRH would result in the release of FSH from which structure? -
ANS-Anterior pituitary
Leuprolide stimulates secretion from which structure? - ANS-Anterior pituitary
Ganirelix inhibits secretion from which structure? - ANS-Hypothalamus
The hormone used to artificially induce labor in pregnant women is naturally stored and
release by which structure? - ANS-Posterior pituitary
A lack of which hormone would result in the elimination of abnormally large amounts of
urine? - ANS-Vasopressin
Which compound would be more appropriate for treating hemophilia A in a patient with
high blood pressure? - ANS-Desmopressin
Through which receptors does desmopressin exert the majority of its effects? - ANS-V2
, What structure produces corticosteroids? - ANS-Adrenal gland
Cortisol production (or administration) produces a feedback loop that effects its own
production. Is this a positive- or negative-feedback loop? - ANS-Negative
Where are glucocorticoid receptors located? - ANS-Intracellularly
Do corticosteroids generally increase or decrease immune and inflammatory response?
- ANS-Decrease
Are larger doses of corticosteroids required for replacement therapy or to achieve an
anti-inflammatory response? - ANS-Anti-inflammatory response
A patient with adrenal insufficiency is being prescribed oral hydrocortisone as a
monotherapy. Which form of insufficiency do they likely have? - ANS-Secondary adrenal
insufficiency
What glucocorticoid is available OTC to treat allergic reactions to mosquito bites? -
ANS-Hydrocortisone
What can cause glucocorticoid related toxicity? - ANS-Both continued use and
withdrawal of glucocorticoids
Which drug would be used to treat mineralocorticoid insufficiency? -
ANS-Fludrocortisone
What drugs would be used to treat elevated levels of mineralocorticoids? -
ANS-Spironolactone
What do the 3 and 4 denote in the thyroid hormones T3and T4? - ANS-Their number of
iodine atoms
A patient suffering from a thyroid disorder that feels constantly exhausted is most likely
suffering from which condition? - ANS-Hashimoto's thyroiditis
Which form of hyperthyroidism is an autoimmune disease? - ANS-Graves' disease
Which form of hyperthyroidism is treated almost exclusively through symptom
management? - ANS-Subacute thyroiditis
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