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BIOL2200 Exam Review 100% Correct Answers Verified Latest 2024 Version

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BIOL2200 Exam Review | 100% Correct Answers | Verified | Latest 2024 Version Question 1. What is modern cell biology? - An integrated discipline that includes cell culture, microscopy, molecular biology, genetics, and biochemistry. Question 2. What is gene ontology? - A major bioinformatics ini...

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  • June 15, 2024
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BIOL2200 Exam Review | 100% Correct
Answers | Verified | Latest 2024 Version
Question 1. What is modern cell biology? - ✔✔An integrated discipline that includes cell culture,
microscopy, molecular biology, genetics, and biochemistry.



Question 2. What is gene ontology? - ✔✔A major bioinformatics initiative to unify the representation of
gene and gene product (i.e. proteins and RNA) attributes. The project includes development of a
controlled vocabulary of a protein's attributes.



Question 3. What are the three domains of gene ontology? Briefly describe them. - ✔✔Cellular
component - the parts of a cell which the protein associates with i.e. where

Molecular function - the elemental activities of a protein at the molecular level, such as binding or
catalysis i.e. what

Biological process - operations or sets of molecular events with a defined beginning and end, pertinent
to the functioning of integrated living units: cells, tissues, organs, and organisms.



Question 4. Name the key structural components of a prokaryotic cell. - ✔✔Outer membrane, Cell wall,
Periplasmic space, Inner membrane, Nucleoid



Question 5. Name the key structural components of a eukaryotic cell. - ✔✔Plasma membrane, Golgi
vesicles, Mitochondrion, Peroxisome, Lysosome, Secretory vesicle, Rough and smooth endoplasmic
reticulum, Nuclear membrane, Nucleus



Question 6. Why is subcellular localisation of proteins essential? - ✔✔Critical to understand function of
individual proteins. As proteins must be targeted to the appropriate compartment to ensure proper
function —> find out where that compartment is/what the proper function is.



Question 7. What is the central dogma of molecular biology? - ✔✔DNA to RNA to Protein



Question 8. What does gene expression dictate? - ✔✔Cell identity and function

, Question 9. What is a cell? - ✔✔Membrane-bound structure containing biomolecules

Structural, functional and biological unit of all organisms



Question 10. What are exons? - ✔✔Protein coding sequence



Question 11. What are introns? - ✔✔Non-coding sequence

Regulatory elements that get spliced out later



Question 12. What is a diploid organism? - ✔✔Two copies of every gene



Question 13. What is an allele? - ✔✔Different versions of same gene



Question 14. What is a polymorphism? - ✔✔Difference in DNA that occurs normally. Doesn't necessarily
change proteins.



Question 15. Describe the process of DNA transcription. - ✔✔1. Transcription, 5' capping

2. Cleavage at poly(A) site

3. Polyadenylation

3. RNA splicing

Genes typically have untranslated areas at 3' and 5' ends

Occurs in nucleus as mRNA has to be transported out of nucleus to be translated



Question 16. What is the most common start codon? - ✔✔ATG



Question 17. What is a cap? - ✔✔Important recognition site for proteins



Question 18. What is polyadenylation? - ✔✔Addition of a poly(A) tail to a messenger RNA

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